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Potential of mucoadhesive chitosan glutamate microparticles as microbicide carriers – antiherpes activity and penetration behavior across the human vaginal epithelium
Chitosan glutamate (gCS) spray-dried microparticles appear promising carriers to overcome challenges associated with vaginal microbicide delivery. This study aimed at elucidating the penetration and mucoadhesive behavior of developed gCS multiunit carriers with zidovudine (ZVD) as a model antiretrov...
Autores principales: | Szymańska, Emilia, Krzyżowska, Małgorzata, Cal, Krzysztof, Mikolaszek, Barbara, Tomaszewski, Jakub, Wołczyński, Sławomir, Winnicka, Katarzyna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8530489/ https://www.ncbi.nlm.nih.gov/pubmed/34668816 http://dx.doi.org/10.1080/10717544.2021.1992037 |
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