Micronucleus production, activation of DNA damage response and cGAS-STING signaling in syncytia induced by SARS-CoV-2 infection

SARS-CoV-2 infection could cause severe acute respiratory syndrome, largely attributed to dysregulated immune activation and extensive lung tissue damage. However, the underlying mechanisms are not fully understood. Here, we reported that viral infection could induce syncytia formation within cells...

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Detalles Bibliográficos
Autores principales: Ren, He, Ma, Chaobing, Peng, Haoran, Zhang, Bo, Zhou, Lulin, Su, Yan, Gao, Xiaoyan, Huang, Hongyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8530504/
https://www.ncbi.nlm.nih.gov/pubmed/34674770
http://dx.doi.org/10.1186/s13062-021-00305-7

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