Cargando…

Genome-wide Association Study of Estradiol Levels and the Causal Effect of Estradiol on Bone Mineral Density

CONTEXT: Estradiol is the primary female sex hormone and plays an important role for skeletal health in both sexes. Several enzymes are involved in estradiol metabolism, but few genome-wide association studies (GWAS) have been performed to characterize the genetic contribution to variation in estrog...

Descripción completa

Detalles Bibliográficos
Autores principales:	Schmitz, Daniel, Ek, Weronica E, Berggren, Elin, Höglund, Julia, Karlsson, Torgny, Johansson, Åsa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2021
Materias:	Online Only Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8530739/ https://www.ncbi.nlm.nih.gov/pubmed/34255042 http://dx.doi.org/10.1210/clinem/dgab507

Ejemplares similares

Corrigendum to: Genome-wide Association Study of Estradiol Levels and the Causal Effect of Estradiol on Bone Mineral Density
Publicado: (2021)

Investigating the Effect of Estradiol Levels on the Risk of Breast, Endometrial, and Ovarian Cancer
por: Johansson, Åsa, et al.
Publicado: (2022)

Causal effects of inflammatory protein biomarkers on inflammatory diseases
por: Ek, Weronica E., et al.
Publicado: (2021)

Low Progesterone and Low Estradiol Levels Associate With Abdominal Aortic Aneurysms in Men
por: Ohlsson, Claes, et al.
Publicado: (2021)

Estradiol and HDL Function in Women – A Partnership for Life
por: Beazer, Jack D, et al.
Publicado: (2021)

Gene-Based Variant Analysis of Whole-Exome Sequencing in Relation to Eosinophil Count
por: Höglund, Julia, et al.
Publicado: (2022)

Endogenous DHEAS Is Causally Linked With Lumbar Spine Bone Mineral Density and Forearm Fractures in Women
por: Quester, Johan, et al.
Publicado: (2021)

Bone Mineral Density After Transitioning From Denosumab to Alendronate
por: Kendler, David, et al.
Publicado: (2019)

Improved power and precision with whole genome sequencing data in genome-wide association studies of inflammatory biomarkers
por: Höglund, Julia, et al.
Publicado: (2019)

Serum Estradiol and 20 Site-Specific Cancers in Women: Mendelian Randomization Study
por: Larsson, Susanna C, et al.
Publicado: (2021)

Genome-wide association study of body fat distribution identifies adiposity loci and sex-specific genetic effects
por: Rask-Andersen, Mathias, et al.
Publicado: (2019)

Genome-wide association analysis of 350 000 Caucasians from the UK Biobank identifies novel loci for asthma, hay fever and eczema
por: Johansson, Åsa, et al.
Publicado: (2019)

Transgender Girls Grow Tall: Adult Height Is Unaffected by GnRH Analogue and Estradiol Treatment
por: Boogers, Lidewij Sophia, et al.
Publicado: (2022)

Elinzanetant (NT-814), a Neurokinin 1,3 Receptor Antagonist, Reduces Estradiol and Progesterone in Healthy Women
por: Pawsey, Steve, et al.
Publicado: (2021)

Gene-environment interaction study for BMI reveals interactions between genetic factors and physical activity, alcohol consumption and socioeconomic status
por: Rask-Andersen, Mathias, et al.
Publicado: (2017)

Fractures, Bone Mineral Density, and Final Height in Craniopharyngioma Patients with a Follow-up of 16 Years
por: van Santen, Selveta S, et al.
Publicado: (2020)

Bones and Crohn's: Estradiol deficiency in men with Crohn's disease is not associated with reduced bone mineral density
por: Klaus, J, et al.
Publicado: (2008)

Genetic Determinants of Circulating Estrogen Levels and Evidence of a Causal Effect of Estradiol on Bone Density in Men
por: Eriksson, Anna L, et al.
Publicado: (2018)

Oral ethinyl estradiol treatment in women with cystic fibrosis is associated with lower bone mineral density
por: Wu, Malinda, et al.
Publicado: (2020)

Contribution of rare whole-genome sequencing variants to plasma protein levels and the missing heritability
por: Kierczak, Marcin, et al.
Publicado: (2022)

Serum Estradiol Levels Are Inversely Associated With Cortical Porosity in Older Men
por: Vandenput, Liesbeth, et al.
Publicado: (2014)

Cognitive Function of Children and Adolescents With Congenital Adrenal Hyperplasia: Importance of Early Diagnosis
por: Messina, Valeria, et al.
Publicado: (2020)

Relationship between Bone Mineral Density and Maturity Index in Cervical Smears, Serum Estradiol Levels and Body Mass Index
por: Sheikholeslami, Homayoun, et al.
Publicado: (2013)

The Causal Relationship Between Sleep and Obesity: Novel Insights and Therapeutic Target
por: Wang, Jun, et al.
Publicado: (2022)

The relative contribution of DNA methylation and genetic variants on protein biomarkers for human diseases
por: Ahsan, Muhammad, et al.
Publicado: (2017)

A Deeper Understanding of the Causal Relationships Between Thyroid Function and Atrial Fibrillation
por: Kuś, Aleksander, et al.
Publicado: (2021)

Comparisons of Immunoassay and Mass Spectrometry Measurements of Serum Estradiol Levels and Their Influence on Clinical Association Studies in Men
por: Ohlsson, Claes, et al.
Publicado: (2013)

Causal Association Between Serum Thyrotropin and Obesity: A Bidirectional, Mendelian Randomization Study
por: Wang, Xichang, et al.
Publicado: (2021)

Causal Associations Between Circulating Adipokines and Cardiovascular Disease: A Mendelian Randomization Study
por: Chen, Delong, et al.
Publicado: (2022)

Levels of serum estradiol and lifestyle factors related with bone mineral density in premenopausal Mexican women: a cross-sectional analysis
por: Huitrón-Bravo, Gerardo, et al.
Publicado: (2016)

BMD-Related Genetic Risk Scores Predict Site-Specific Fractures as Well as Trabecular and Cortical Bone Microstructure
por: Nethander, Maria, et al.
Publicado: (2020)

Understanding the Link Between Obesity and Severe COVID-19 Outcomes: Causal Mediation by Systemic Inflammatory Response
por: Foulkes, Andrea S, et al.
Publicado: (2021)

PB2151: EVALUATION OF BONE MINERAL DENSITY IN LYMPHOMA PATIENTS WITH USING PET/CT AND THE ROLE OF BCL-2
por: Okan, V., et al.
Publicado: (2022)

Effects of Potassium or Sodium Supplementation on Mineral Homeostasis: A Controlled Dietary Intervention Study
por: Humalda, Jelmer K, et al.
Publicado: (2020)

Genetic Support of A Causal Relationship Between Iron Status and Type 2 Diabetes: A Mendelian Randomization Study
por: Wang, Xinhui, et al.
Publicado: (2021)

Cohort Profile Update: The HUNT Study, Norway
por: Åsvold, Bjørn Olav, et al.
Publicado: (2022)

Cohort Profile: The Africa Medical and Behavioral Sciences Organization (AMBSO) Population Health Surveillance (APHS) in rural, semi-urban and urban Uganda
por: Mugamba, Stephen, et al.
Publicado: (2022)

Association between serum estradiol level, sex hormone binding globulin level, and bone mineral density in middle-aged postmenopausal women
por: Zhu, Zhongxin, et al.
Publicado: (2021)

Comparison the Effect of Ferutinin and 17β-Estradiol on Bone Mineralization of Developing Zebrafish (Danio rerio) Larvae
por: Zare Mirakabad, Hoda, et al.
Publicado: (2019)

Cohort Profile: The 100 Million Brazilian Cohort
por: Barreto, Mauricio L, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_e1n4p15vivfrok2s7isfm8t0ub