Oncogenic HSP90 Facilitates Metabolic Alterations in Aggressive B-cell Lymphomas

HSP90 is critical for maintenance of the cellular proteostasis. In cancer cells, HSP90 also becomes a nucleating site for the stabilization of multiprotein complexes including signaling pathways and transcription complexes. Here we described the role of this HSP90 form, referred to as oncogenic HSP9...

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Detalles Bibliográficos
Autores principales: Calvo-Vidal, M. Nieves, Zamponi, Nahuel, Krumsiek, Jan, Stockslager, Max A., Revuelta, Maria V., Phillip, Jude M., Marullo, Rossella, Tikhonova, Ekaterina, Kotlov, Nikita, Patel, Jayeshkumar, Yang, Shao Ning, Yang, Lucy, Taldone, Tony, Thieblemont, Catherine, Leonard, John P., Martin, Peter, Inghirami, Giorgio, Chiosis, Gabriela, Manalis, Scott R., Cerchietti, Leandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2021
Materias:
Metabolism and Chemical Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8530929/
https://www.ncbi.nlm.nih.gov/pubmed/34479963
http://dx.doi.org/10.1158/0008-5472.CAN-21-2734

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