Direct reprogramming induces vascular regeneration post muscle ischemic injury

Reprogramming non-cardiomyocytes (non-CMs) into cardiomyocyte (CM)-like cells is a promising strategy for cardiac regeneration in conditions such as ischemic heart disease. Here, we used a modified mRNA (modRNA) gene delivery platform to deliver a cocktail, termed 7G-modRNA, of four cardiac-reprogra...

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Detalles Bibliográficos
Autores principales: Kaur, Keerat, Hadas, Yoav, Kurian, Ann Anu, Żak, Magdalena M., Yoo, Jimeen, Mahmood, Asharee, Girard, Hanna, Komargodski, Rinat, Io, Toshiro, Santini, Maria Paola, Sultana, Nishat, Sharkar, Mohammad Tofael Kabir, Magadum, Ajit, Fargnoli, Anthony, Yoon, Seonghun, Chepurko, Elena, Chepurko, Vadim, Eliyahu, Efrat, Pinto, Dalila, Lebeche, Djamel, Kovacic, Jason C., Hajjar, Roger J., Rafii, Shahin, Zangi, Lior
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8531157/
https://www.ncbi.nlm.nih.gov/pubmed/34332145
http://dx.doi.org/10.1016/j.ymthe.2021.07.014

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