Comparative epigenetic analysis of tumour initiating cells and syngeneic EPSC-derived neural stem cells in glioblastoma

Epigenetic mechanisms which play an essential role in normal developmental processes, such as self-renewal and fate specification of neural stem cells (NSC) are also responsible for some of the changes in the glioblastoma (GBM) genome. Here we develop a strategy to compare the epigenetic and transcr...

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Detalles Bibliográficos
Autores principales: Vinel, Claire, Rosser, Gabriel, Guglielmi, Loredana, Constantinou, Myrianni, Pomella, Nicola, Zhang, Xinyu, Boot, James R., Jones, Tania A., Millner, Thomas O., Dumas, Anaelle A., Rakyan, Vardhman, Rees, Jeremy, Thompson, Jamie L., Vuononvirta, Juho, Nadkarni, Suchita, El Assan, Tedani, Aley, Natasha, Lin, Yung-Yao, Liu, Pentao, Nelander, Sven, Sheer, Denise, Merry, Catherine L. R., Marelli-Berg, Federica, Brandner, Sebastian, Marino, Silvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8531305/
https://www.ncbi.nlm.nih.gov/pubmed/34675201
http://dx.doi.org/10.1038/s41467-021-26297-6

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