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Two-level modeling approach to identify the regulatory dynamics capturing drug response heterogeneity in single-cells
Single-cell multimodal technologies reveal the scales of cellular heterogeneity impairing cancer treatment, yet cell response dynamics remain largely underused to decipher the mechanisms of drug resistance they take part in. As the phenotypic heterogeneity of a clonal cell population informs on the...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8531316/ https://www.ncbi.nlm.nih.gov/pubmed/34675364 http://dx.doi.org/10.1038/s41598-021-99943-0 |