Cargando…

Optimal value of CA19-9 determined by KRAS-mutated circulating tumor DNA contributes to the prediction of prognosis in pancreatic cancer patients

Despite the acceptance of carbohydrate antigen 19-9 (CA19-9) as a valuable predictor for the prognosis of pancreatic ductal adenocarcinoma (PDAC), its cutoff value remains controversial. Our previous study showed a significant correlation between CA19-9 levels and the presence of KRAS-mutated ctDNA...

Descripción completa

Detalles Bibliográficos
Autores principales:	Watanabe, Fumiaki, Suzuki, Koichi, Tamaki, Sawako, Abe, Iku, Endo, Yuhei, Takayama, Yuji, Ishikawa, Hideki, Kakizawa, Nao, Saito, Masaaki, Futsuhara, Kazushige, Noda, Hiroshi, Konishi, Fumio, Rikiyama, Toshiki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8531317/ https://www.ncbi.nlm.nih.gov/pubmed/34675229 http://dx.doi.org/10.1038/s41598-021-00060-9

Ejemplares similares

Longitudinal monitoring of KRAS-mutated circulating tumor DNA enables the prediction of prognosis and therapeutic responses in patients with pancreatic cancer
por: Watanabe, Fumiaki, et al.
Publicado: (2019)

Temporary loss of consciousness during cetuximab treatment of a patient with metastatic colon cancer: a case report
por: Fukui, Taro, et al.
Publicado: (2019)

Prophylactic use of pegfilgrastim enables the management of severe neutropenia without dose delays in patients with metastatic colorectal cancer treated with TAS-102 plus bevacizumab
por: Tamaki, Sawako, et al.
Publicado: (2022)

Genome-wide DNA hypomethylation drives a more invasive pancreatic cancer phenotype and has predictive occult distant metastasis and prognosis potential
por: Endo, Yuhei, et al.
Publicado: (2022)

Monitoring circulating tumor DNA revealed dynamic changes in KRAS status in patients with metastatic colorectal cancer
por: Takayama, Yuji, et al.
Publicado: (2018)

Overexpression of satellite RNAs in heterochromatin induces chromosomal instability and reflects drug sensitivity in mouse cancer cells
por: Tamaki, Sawako, et al.
Publicado: (2022)

Enhancement of DNA hypomethylation alterations by gastric and bile acids promotes chromosomal instability in Barrett’s epithelial cell line
por: Abe, Iku, et al.
Publicado: (2022)

Circulating tumor DNA in molecular assessment feasibly predicts early progression of pancreatic cancer that cannot be identified via initial imaging
por: Watanabe, Fumiaki, et al.
Publicado: (2023)

Morphological response contributes to patient selection for rescue liver resection in chemotherapy patients with initially un-resectable colorectal liver metastasis
por: Suzuki, Koichi, et al.
Publicado: (2017)

En bloc pancreaticoduodenectomy and right hemicolectomy for locally advanced right-sided colon cancer
por: Kaneda, Yuji, et al.
Publicado: (2017)

Mid-term Efficacy of Local Repair Using Modified Altemeier Technique for Stomal Prolapse: A Case Series
por: Tsujinaka, Shingo, et al.
Publicado: (2022)

Drain output volume after pancreaticoduodenectomy is a useful warning sign for postoperative complications
por: Fukui, Taro, et al.
Publicado: (2021)

The surgical treatment of acute and severe diversion colitis mimicking ulcerative colitis: a case report
por: Kakizawa, Nao, et al.
Publicado: (2018)

Effect of Antithrombotic Therapy on Secondary Bleeding After Proctological Surgery
por: Maemoto, Ryo, et al.
Publicado: (2021)

Indications and Outcomes of a Hybrid Method Combining Laparoscopic and Anterior Approaches for Inguinal Hernia Repair
por: Kakizawa, Nao, et al.
Publicado: (2022)

Intussusception secondary to descending colon lipoma presenting with simultaneous acute appendicitis
por: Kikuchi, Nozomi, et al.
Publicado: (2018)

Efficacy of Neoadjuvant Chemotherapy with Capecitabine plus Oxaliplatin in the Treatment of Locally Advanced Sigmoid Colon Cancer Invading the Urinary Bladder: A Report of Three Cases
por: Takenami, Tsutomu, et al.
Publicado: (2019)

Ileectomy performed on a case of adult intussusception due to inversion of Meckel’s diverticulum
por: Abe, Iku, et al.
Publicado: (2020)

Superiority trial comparing intraoperative wound irrigation with aqueous 10% povidone–iodine to saline for the purpose of reducing surgical site infection after elective gastrointestinal surgery: study protocol for a randomised controlled trial
por: Maemoto, Ryo, et al.
Publicado: (2021)

Early peritoneal metastasis after laparoscopic incisional hernia repair secondary to colon cancer resection: A case report
por: Machida, Erika, et al.
Publicado: (2021)

IκBζ regulates the development of nonalcoholic fatty liver disease through the attenuation of hepatic steatosis in mice
por: Ishikawa, Hideki, et al.
Publicado: (2022)

Liquid biopsy leads to a paradigm shift in the treatment of pancreatic cancer
por: Watanabe, Fumiaki, et al.
Publicado: (2022)

A case of corrosive esophagitis causing extensive cicatricial esophageal stenosis treated by esophageal bypass with supercharged pedicled jejunal pull-up
por: Saito, Masaaki, et al.
Publicado: (2019)

Minimally invasive esophagectomy in the semi-prone position for corrosive esophagitis: a case report
por: Obitsu, Tamotsu, et al.
Publicado: (2022)

Intestinal perforation secondary to intestinal Burkitt lymphoma
por: Takayama, Yuji, et al.
Publicado: (2021)

Surgical Resection with Neoadjuvant Chemotherapy for Locoregionally Recurrent Appendiceal Cancer Invading the External Iliac Vessels
por: Takahashi, Jun, et al.
Publicado: (2018)

Successful treatment of recurrent stoma prolapse after Hartmann’s procedure through ileorectal anastomosis: A case report
por: Takayama, Noriya, et al.
Publicado: (2017)

DNA methylation alterations of AXIN2 in serrated adenomas and colon carcinomas with microsatellite instability
por: Muto, Yuta, et al.
Publicado: (2014)

Laparoscopic and percutaneous repair of a large midline incisional hernia extending to the bilateral subcostal region: A case report
por: Tsujinaka, Shingo, et al.
Publicado: (2018)

Bevacizumab is associated with delayed anastomotic leak after low anterior resection with preoperative radiotherapy for rectal cancer: a case report
por: Machida, Erika, et al.
Publicado: (2019)

Large Brunner's Gland Hyperplasia with Bleeding: A Case Report
por: Okutomi, Yuki, et al.
Publicado: (2021)

Treatment of stage IV gastric cancer with induction chemotherapy using S-1 and cisplatin followed by curative resection in selected patients
por: Saito, Masaaki, et al.
Publicado: (2014)

Multiple primary malignancies involving primary sporadic colorectal cancer in Japan: incidence of gastric cancer with colorectal cancer patients may be higher than previously recognized
por: Kato, Takaharu, et al.
Publicado: (2015)

Anal fistula metastasis of rectal cancer after neoadjuvant therapy: a case report
por: Fukai, Shota, et al.
Publicado: (2022)

Acute fulminant pseudomembranous colitis which developed after ileostomy closure and required emergent total colectomy: a case report
por: Abe, Iku, et al.
Publicado: (2012)

Clinical characteristics of synchronous colorectal cancers in Japan
por: Kato, Takaharu, et al.
Publicado: (2016)

Successful mesh plug repair using a hybrid method for recurrent inguinal hernia after laparoscopic transabdominal preperitoneal approach: A case report
por: Kikugawa, Rina, et al.
Publicado: (2019)

The advantage of laparoscopic surgery in the treatment of Spigelian hernia: A report of two cases
por: Takayama, Yuji, et al.
Publicado: (2021)

Current Management of Intestinal Stomas and Their Complications
por: Tsujinaka, Shingo, et al.
Publicado: (2020)

A case of needle tract seeding that seemed to be caused by endoscopic ultrasound‐guided fine‐needle aspiration
por: Sekine, Masanari, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_uedkh0ndc1b47n6njc985pob64