Cargando…
GJB2 gene therapy and conditional deletion reveal developmental stage-dependent effects on inner ear structure and function
Pathogenic variants in GJB2, the gene encoding connexin 26, are the most common cause of autosomal-recessive hereditary deafness. Despite this high prevalence, pathogenic mechanisms leading to GJB2-related deafness are not well understood, and cures are absent. Humans with GJB2-related deafness reta...
| Autores principales: | , , , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society of Gene & Cell Therapy
2021
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8531464/ https://www.ncbi.nlm.nih.gov/pubmed/34729379 http://dx.doi.org/10.1016/j.omtm.2021.09.009 |