Cargando…

NOVA1-Mediated SORBS2 Isoform Promotes Colorectal Cancer Migration by Activating the Notch Pathway

Background: Gene expression and alternative splicing (AS) can promote cancer development via complex mechanisms. We aimed to identify and verify the hub AS events and splicing factors associated with the progression of colorectal cancer (CRC). Methods: RNA-Seq data, clinical data, and AS events of 5...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Tao, Chen, Sixia, Peng, Yi, Wang, Changgang, Cheng, Xi, Zhao, Ren, Liu, Kun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Cell and Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8531477/ https://www.ncbi.nlm.nih.gov/pubmed/34692669 http://dx.doi.org/10.3389/fcell.2021.673873

Ejemplares similares

Identification and verification of a prognostic signature based on a miRNA–mRNA interaction pattern in colon adenocarcinoma
por: Zhao, Qiwu, et al.
Publicado: (2023)

NOVA regulates Dcc alternative splicing during neuronal migration and axon guidance in the spinal cord
por: Leggere, Janelle C, et al.
Publicado: (2016)

Notch signaling restricts FGF pathway activation in parapineal cells to promote their collective migration
por: Wei, Lu, et al.
Publicado: (2019)

SNORA72 Activates the Notch1/c-Myc Pathway to Promote Stemness Transformation of Ovarian Cancer Cells
por: Zhang, Liwen, et al.
Publicado: (2020)

Notch receptor/ligand diversity: contribution to colorectal cancer stem cell heterogeneity
por: Brisset, Morgan, et al.
Publicado: (2023)

Corrigendum: SNORA72 activates the Notch1/c-Myc pathway to promote stemness transformation of ovarian cancer cells
por: Zhang, Liwen, et al.
Publicado: (2022)

Hypoxia Activates Notch4 via ERK/JNK/P38 MAPK Signaling Pathways to Promote Lung Adenocarcinoma Progression and Metastasis
por: Li, Xiaochen, et al.
Publicado: (2021)

The Role of Notch, Hedgehog, and Wnt Signaling Pathways in the Resistance of Tumors to Anticancer Therapies
por: Kumar, Vivek, et al.
Publicado: (2021)

SORBS2 upregulation may contribute to dysfunction in LVNC via the Notch pathway: SORBS2 upregulation contributes to dysfunction
por: Li, Chunyan, et al.
Publicado: (2022)

SORBS2 is a genetic factor contributing to cardiac malformation of 4q deletion syndrome patients
por: Liang, Fei, et al.
Publicado: (2021)

Integrins control epithelial stem cell proliferation in the Drosophila ovary by modulating the Notch pathway
por: Rincón-Ortega, Lourdes, et al.
Publicado: (2023)

Interleukin 37 Suppresses M1 Macrophage Polarization Through Inhibition of the Notch1 and Nuclear Factor Kappa B Pathways
por: Zhou, Peitao, et al.
Publicado: (2020)

Increased Expression of Fibulin-1 Is Associated With Hepatocellular Carcinoma Progression by Regulating the Notch Signaling Pathway
por: Gong, Jiao, et al.
Publicado: (2020)

Interplay Between Notch and YAP/TAZ Pathways in the Regulation of Cell Fate During Embryo Development
por: Engel-Pizcueta, Carolyn, et al.
Publicado: (2021)

Turn It Down a Notch
por: Carrieri, Francesca A., et al.
Publicado: (2017)

Extracellular Vesicles From Notch Activated Cardiac Mesenchymal Stem Cells Promote Myocyte Proliferation and Neovasculogenesis
por: Xuan, Wanling, et al.
Publicado: (2020)

TILRR Promotes Migration of Immune Cells Through Induction of Soluble Inflammatory Mediators
por: Kashem, Mohammad Abul, et al.
Publicado: (2020)

Biological Significance of NOTCH Signaling Strength
por: Shen, Wei, et al.
Publicado: (2021)

Vascular Notch Signaling in Stress Hematopoiesis
por: Huang, Can, et al.
Publicado: (2021)

Notch Signalling in Breast Development and Cancer
por: Edwards, Abigail, et al.
Publicado: (2021)

STX2 Promotes Trophoblast Growth, Migration, and Invasion Through Activation of the PI3K-AKT Pathway in Preeclampsia
por: Li, Yan, et al.
Publicado: (2021)

Notch Signaling in Vascular Endothelial Cells, Angiogenesis, and Tumor Progression: An Update and Prospective
por: Akil, Abdellah, et al.
Publicado: (2021)

Long Non-coding RNAs LOC100126784 and POM121L9P Derived From Bone Marrow Mesenchymal Stem Cells Enhance Osteogenic Differentiation via the miR-503-5p/SORBS1 Axis
por: Xu, Yiyang, et al.
Publicado: (2021)

Notch signaling sculpts the stem cell niche
por: Zamfirescu, Ana-Maria, et al.
Publicado: (2022)

Recent advances in in situ Notch signaling measurement
por: Yoshihara, Masaharu, et al.
Publicado: (2023)

Functional Gene Expression Differentiation of the Notch Signaling Pathway in Female Reproductive Tract Tissues—A Comprehensive Review With Analysis
por: Orzechowska, Magdalena, et al.
Publicado: (2020)

Bruton’s Tyrosine Kinase and Its Isoforms in Cancer
por: Wang, Xianhui, et al.
Publicado: (2021)

HMGB3 is a Potential Therapeutic Target by Affecting the Migration and Proliferation of Colorectal Cancer
por: Gong, Wenjing, et al.
Publicado: (2022)

Immune Cell Plasticity Allows for Resetting of Phenotype From Effector to Regulator With Combined Inhibition of Notch/eIF5A Pathways
por: Imam, Shahnawaz, et al.
Publicado: (2021)

SCRIB Promotes Proliferation and Metastasis by Targeting Hippo/YAP Signalling in Colorectal Cancer
por: Shen, Hengyang, et al.
Publicado: (2021)

Profilin Isoforms in Health and Disease – All the Same but Different
por: Murk, Kai, et al.
Publicado: (2021)

Cancer-Associated Fibroblasts Promote Migration and Invasion of Non-Small Cell Lung Cancer Cells via miR-101-3p Mediated VEGFA Secretion and AKT/eNOS Pathway
por: Guo, Xueru, et al.
Publicado: (2021)

Segmentally Demineralized Cortical Bone With Stem Cell-Derived Matrix Promotes Proliferation, Migration and Differentiation of Stem Cells in vitro
por: He, Shu-Kun, et al.
Publicado: (2022)

Cancer-Associated Fibroblast-Derived Interleukin-8 Promotes Ovarian Cancer Cell Stemness and Malignancy Through the Notch3-Mediated Signaling
por: Ji, Zhaodong, et al.
Publicado: (2021)

RNF180 Inhibits Proliferation and Promotes Apoptosis of Colorectal Cancer Through Ubiquitination of WISP1
por: Wei, Feng, et al.
Publicado: (2021)

The role of the ERK signaling pathway in promoting angiogenesis for treating ischemic diseases
por: Song, Yue-Yue, et al.
Publicado: (2023)

PINCH1 Promotes Fibroblast Migration in Extracellular Matrices and Influences Their Mechanophenotype
por: Mierke, Claudia Tanja, et al.
Publicado: (2022)

Therapeutic Targeting of Notch Signaling: From Cancer to Inflammatory Disorders
por: Allen, Frederick, et al.
Publicado: (2021)

Autocrine VEGF Isoforms Differentially Regulate Endothelial Cell Behavior
por: Yamamoto, Hideki, et al.
Publicado: (2016)

Aerobic Glycolysis in the Retina: Functional Roles of Pyruvate Kinase Isoforms
por: Rajala, Raju V. S.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_bqvlpg43boj513mpll1oa97d4j