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Nanoscale Organisation of Ryanodine Receptors and Junctophilin-2 in the Failing Human Heart

The disrupted organisation of the ryanodine receptors (RyR) and junctophilin (JPH) is thought to underpin the transverse tubule (t-tubule) remodelling in a failing heart. Here, we assessed the nanoscale organisation of these two key proteins in the failing human heart. Recently, an advanced feature...

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Detalles Bibliográficos
Autores principales: Hou, Yufeng, Bai, Jizhong, Shen, Xin, de Langen, Oscar, Li, Amy, Lal, Sean, dos Remedios, Cristobal G., Baddeley, David, Ruygrok, Peter N., Soeller, Christian, Crossman, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8531480/
https://www.ncbi.nlm.nih.gov/pubmed/34690801
http://dx.doi.org/10.3389/fphys.2021.724372