Role of the Tyrosine Phosphatase SHP-2 in Mediating Adrenomedullin Proangiogenic Activity in Solid Tumors

VE-cadherin is an essential adhesion molecule in endothelial adherens junctions, and the integrity of these complexes is thought to be regulated by VE-cadherin tyrosine phosphorylation. We have previously shown that adrenomedullin (AM) blockade correlates with elevated levels of phosphorylated VE-ca...

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Detalles Bibliográficos
Autores principales: Sigaud, Romain, Dussault, Nadège, Berenguer-Daizé, Caroline, Vellutini, Christine, Benyahia, Zohra, Cayol, Mylène, Parat, Fabrice, Mabrouk, Kamel, Vázquez, Ramiro, Riveiro, Maria E., Metellus, Philippe, Ouafik, L’Houcine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8531523/
https://www.ncbi.nlm.nih.gov/pubmed/34692535
http://dx.doi.org/10.3389/fonc.2021.753244

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