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IL-17A reprograms intestinal epithelial cells to facilitate HIV-1 replication and outgrowth in CD4+ T cells

The crosstalk between intestinal epithelial cells (IECs) and Th17-polarized CD4(+) T cells is critical for mucosal homeostasis, with HIV-1 causing significant alterations in people living with HIV (PLWH) despite antiretroviral therapy (ART). In a model of IEC and T cell co-cultures, we investigated...

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Detalles Bibliográficos
Autores principales:	Wiche Salinas, Tomas Raul, Gosselin, Annie, Raymond Marchand, Laurence, Moreira Gabriel, Etiene, Tastet, Olivier, Goulet, Jean-Philippe, Zhang, Yuwei, Vlad, Dragos, Touil, Hanane, Routy, Jean-Pierre, Bego, Mariana G., El-Far, Mohamed, Chomont, Nicolas, Landay, Alan L., Cohen, Éric A., Tremblay, Cécile, Ancuta, Petronela
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8531570/ https://www.ncbi.nlm.nih.gov/pubmed/34712922 http://dx.doi.org/10.1016/j.isci.2021.103225

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