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Cancer spectrum in TP53-deficient golden Syrian hamsters: A new model for Li-Fraumeni syndrome

BACKGROUND: The TP53 tumor suppressor gene is the most commonly mutated gene in human cancers. Humans who inherit mutant TP53 alleles develop a wide range of early onset cancers, a disorder called Li-Fraumeni Syndrome (LFS). Trp53-deficient mice recapitulate most but not all of the cancer phenotypes...

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Detalles Bibliográficos
Autores principales:	Miao, Jinxin, Li, Rong, Wettere, Arnaud J. Van, Guo, Haoran, Tabaran, Alexandru-Flaviu, O'Sullivan, M. Gerald, Carlson, Timothy, Scott, Patricia M., Chen, Kuisheng, Gao, Dongling, Li, Huixiang, Wang, Yaohe, Wang, Zhongde, Cormier, Robert T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Wolters Kluwer - Medknow 2021
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8531574/ https://www.ncbi.nlm.nih.gov/pubmed/34729050 http://dx.doi.org/10.4103/jcar.jcar_18_21

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