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Outcome of routine histopathological examination of gallbladder specimen following elective laparoscopic cholecystectomy

BACKGROUND: Gallstone disease is one of the commonest surgical ailments encountered in our setup. Its prevalence in India varies from 2% to 29%. Although cholelithiasis accounts for more than 95% of gall bladder related disease, routine histopathological examination (HPE) is vital. It reveals a myri...

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Autores principales: Jha, Ashesh Kumar, Ali, Ashraf, Kumar, Manoj, Bhadani, Punam Prasad, Murthy, Niroop B. S., Chandrakant, Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8531575/
https://www.ncbi.nlm.nih.gov/pubmed/34729051
http://dx.doi.org/10.4103/jcar.jcar_19_21
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author Jha, Ashesh Kumar
Ali, Ashraf
Kumar, Manoj
Kumar, Manoj
Bhadani, Punam Prasad
Murthy, Niroop B. S.
Chandrakant, Kumar
author_facet Jha, Ashesh Kumar
Ali, Ashraf
Kumar, Manoj
Kumar, Manoj
Bhadani, Punam Prasad
Murthy, Niroop B. S.
Chandrakant, Kumar
author_sort Jha, Ashesh Kumar
collection PubMed
description BACKGROUND: Gallstone disease is one of the commonest surgical ailments encountered in our setup. Its prevalence in India varies from 2% to 29%. Although cholelithiasis accounts for more than 95% of gall bladder related disease, routine histopathological examination (HPE) is vital. It reveals a myriad of benign as well as the malignant surgical pathology of the gallbladder (GB). This part of the world is considered as an endemic region for GB carcinoma as well as gallstone disease. This study intends to evaluate the outcome of the routine HPE of laparoscopic cholecystectomy specimens. METHODS: This retrospective observational study evaluated the results of the routine HPE of elective laparoscopic cholecystectomy specimens of single tertiary care center. Patients suspected or diagnosed with carcinoma gall bladder were excluded. Demographic data such as age, sex, and pathology results were recorded. RESULTS: From January 2017 to December 2019, HPEs of 921 patients who had undergone laparoscopic cholecystectomy specimens were analyzed. 97.6% specimens had benign lesion of which chronic calculus cholecystitis was predominantly high (95.01%) followed by cholesterosis (9.9%) and xanthogranulomatous cholecystitis (6.51%). Incidental carcinoma gall bladder was observed in 17 specimens accounting for 1.85%. Mean age of patients who underwent cholecystectomy was 43.10 ± 13.90 with female to male ratio of 3.23:1. CONCLUSION: Chronic calculus cholecystitis was the most common gall bladder disease with high female preponderance to all GB pathologies. This study affirms the importance of routine HPE after cholecystectomy as early incidental detection of carcinoma gall bladder alters the postoperative management approach and patients are expected to have a better outcome with it.
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spelling pubmed-85315752021-11-01 Outcome of routine histopathological examination of gallbladder specimen following elective laparoscopic cholecystectomy Jha, Ashesh Kumar Ali, Ashraf Kumar, Manoj Kumar, Manoj Bhadani, Punam Prasad Murthy, Niroop B. S. Chandrakant, Kumar J Carcinog Original Article BACKGROUND: Gallstone disease is one of the commonest surgical ailments encountered in our setup. Its prevalence in India varies from 2% to 29%. Although cholelithiasis accounts for more than 95% of gall bladder related disease, routine histopathological examination (HPE) is vital. It reveals a myriad of benign as well as the malignant surgical pathology of the gallbladder (GB). This part of the world is considered as an endemic region for GB carcinoma as well as gallstone disease. This study intends to evaluate the outcome of the routine HPE of laparoscopic cholecystectomy specimens. METHODS: This retrospective observational study evaluated the results of the routine HPE of elective laparoscopic cholecystectomy specimens of single tertiary care center. Patients suspected or diagnosed with carcinoma gall bladder were excluded. Demographic data such as age, sex, and pathology results were recorded. RESULTS: From January 2017 to December 2019, HPEs of 921 patients who had undergone laparoscopic cholecystectomy specimens were analyzed. 97.6% specimens had benign lesion of which chronic calculus cholecystitis was predominantly high (95.01%) followed by cholesterosis (9.9%) and xanthogranulomatous cholecystitis (6.51%). Incidental carcinoma gall bladder was observed in 17 specimens accounting for 1.85%. Mean age of patients who underwent cholecystectomy was 43.10 ± 13.90 with female to male ratio of 3.23:1. CONCLUSION: Chronic calculus cholecystitis was the most common gall bladder disease with high female preponderance to all GB pathologies. This study affirms the importance of routine HPE after cholecystectomy as early incidental detection of carcinoma gall bladder alters the postoperative management approach and patients are expected to have a better outcome with it. Wolters Kluwer - Medknow 2021-10-08 /pmc/articles/PMC8531575/ /pubmed/34729051 http://dx.doi.org/10.4103/jcar.jcar_19_21 Text en Copyright: © 2021 Journal of Carcinogenesis https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Original Article
Jha, Ashesh Kumar
Ali, Ashraf
Kumar, Manoj
Kumar, Manoj
Bhadani, Punam Prasad
Murthy, Niroop B. S.
Chandrakant, Kumar
Outcome of routine histopathological examination of gallbladder specimen following elective laparoscopic cholecystectomy
title Outcome of routine histopathological examination of gallbladder specimen following elective laparoscopic cholecystectomy
title_full Outcome of routine histopathological examination of gallbladder specimen following elective laparoscopic cholecystectomy
title_fullStr Outcome of routine histopathological examination of gallbladder specimen following elective laparoscopic cholecystectomy
title_full_unstemmed Outcome of routine histopathological examination of gallbladder specimen following elective laparoscopic cholecystectomy
title_short Outcome of routine histopathological examination of gallbladder specimen following elective laparoscopic cholecystectomy
title_sort outcome of routine histopathological examination of gallbladder specimen following elective laparoscopic cholecystectomy
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8531575/
https://www.ncbi.nlm.nih.gov/pubmed/34729051
http://dx.doi.org/10.4103/jcar.jcar_19_21
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