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Distinct conformers of amyloid beta accumulate in the neocortex of patients with rapidly progressive Alzheimer's disease

Amyloid beta (Aβ) deposition in the neocortex is a major hallmark of Alzheimer's disease (AD), but the extent of deposition does not readily explain phenotypic diversity and rate of disease progression. The prion strain–like model of disease heterogeneity suggests the existence of different con...

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Detalles Bibliográficos
Autores principales:	Liu, He, Kim, Chae, Haldiman, Tracy, Sigurdson, Christina J., Nyström, Sofie, Nilsson, K. Peter R., Cohen, Mark L., Wisniewski, Thomas, Hammarström, Per, Safar, Jiri G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8531671/ https://www.ncbi.nlm.nih.gov/pubmed/34599965 http://dx.doi.org/10.1016/j.jbc.2021.101267

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