Structural implications of lipoarabinomannan glycans from global clinical isolates in diagnosis of Mycobacterium tuberculosis infection

In Mycobacterium tuberculosis (Mtb), surface-exposed Lipoarabinomannan (LAM) is a key determinant of immunogenicity, yet its intrinsic heterogeneity confounds typical structure–function analysis. Recently, LAM gained a strong foothold as a validated marker for active tuberculosis (TB) infection and...

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Detalles Bibliográficos
Autores principales: De, Prithwiraj, Amin, Anita G., Flores, Danara, Simpson, Anne, Dobos, Karen, Chatterjee, Delphi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8531672/
https://www.ncbi.nlm.nih.gov/pubmed/34600887
http://dx.doi.org/10.1016/j.jbc.2021.101265

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8531672/
https://www.ncbi.nlm.nih.gov/pubmed/34600887
http://dx.doi.org/10.1016/j.jbc.2021.101265

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