Increased ROS-Dependent Fission of Mitochondria Causes Abnormal Morphology of the Cell Powerhouses in a Murine Model of Amyotrophic Lateral Sclerosis

Amyotrophic lateral sclerosis (ALS) is the most common motor neuron disease in humans and remains to have a fatal prognosis. Recent studies in animal models and human ALS patients indicate that increased reactive oxygen species (ROS) play an important role in the pathogenesis. Considering previous s...

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Detalles Bibliográficos
Autores principales: Stein, Jan, Walkenfort, Bernd, Cihankaya, Hilal, Hasenberg, Mike, Bader, Verian, Winklhofer, Konstanze F., Röderer, Pascal, Matschke, Johann, Theiss, Carsten, Matschke, Veronika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8531774/
https://www.ncbi.nlm.nih.gov/pubmed/34691359
http://dx.doi.org/10.1155/2021/6924251

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