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Dose‐effect relation between regular consumption of 100% cocoa powder and blood pressure in young, healthy black Africans

BACKGROUND: Some previous works have focused on dose‐response relationship between cocoa consumption and blood pressure in Caucasians. As black subjects have lower nitric oxide bioavailability, the aim of this work was to determine the dose‐effect relation between cocoa and blood pressure in black A...

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Autores principales: Balayssac‐Siransy, Edwige, Ouattara, Soualiho, Boka, Kotchi Joël Michée, Ahiboh, Hugues, Yéo, Téniloh Augustin, Yapo, Paule‐Denise, Kondo, Aya Liliane, Touré, Walamitien Cyrille, Edé, Kotchi Fabrice, Dah, Cyrille Serges, Bogui, Pascal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8531838/
https://www.ncbi.nlm.nih.gov/pubmed/34676690
http://dx.doi.org/10.14814/phy2.15070
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author Balayssac‐Siransy, Edwige
Ouattara, Soualiho
Boka, Kotchi Joël Michée
Ahiboh, Hugues
Yéo, Téniloh Augustin
Yapo, Paule‐Denise
Kondo, Aya Liliane
Touré, Walamitien Cyrille
Edé, Kotchi Fabrice
Dah, Cyrille Serges
Bogui, Pascal
author_facet Balayssac‐Siransy, Edwige
Ouattara, Soualiho
Boka, Kotchi Joël Michée
Ahiboh, Hugues
Yéo, Téniloh Augustin
Yapo, Paule‐Denise
Kondo, Aya Liliane
Touré, Walamitien Cyrille
Edé, Kotchi Fabrice
Dah, Cyrille Serges
Bogui, Pascal
author_sort Balayssac‐Siransy, Edwige
collection PubMed
description BACKGROUND: Some previous works have focused on dose‐response relationship between cocoa consumption and blood pressure in Caucasians. As black subjects have lower nitric oxide bioavailability, the aim of this work was to determine the dose‐effect relation between cocoa and blood pressure in black Africans. METHOD: One hundred and thirty healthy black African males aged 18–30 were randomly assigned into four groups: three groups consuming 10 g, 5 g, or 2 g of cocoa powder daily for three weeks and one control group that did not consume cocoa. Systolic blood pressure (SBP), diastolic blood pressure (DBP), and heart rate (HR) were measured on day 1 (D1, before any subject consumed cocoa), D8, D15, and D22. Means of the parameters at each of the four visits and changes of the means were compared among the groups. RESULTS: Significant decrease in SBP was noted in consumers of 10 g compared to controls in the 1st week, and compared to consumers of 2 g in the 2nd and 3rd weeks of follow‐up. Means and changes of DBP were statistically similar among the four groups. CONCLUSION: Among our cohort, decrease in SBP was significantly greater in the heavy cocoa consumer group (10 g) compared to the low consumer group (2 g), but there was no statistically significant difference when compared with the intermediate consumer group (5 g). The dose‐response relationship between cocoa consumption and changes in SBP was not linear. No relationship was found between cocoa consumption and DBP.
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spelling pubmed-85318382021-10-28 Dose‐effect relation between regular consumption of 100% cocoa powder and blood pressure in young, healthy black Africans Balayssac‐Siransy, Edwige Ouattara, Soualiho Boka, Kotchi Joël Michée Ahiboh, Hugues Yéo, Téniloh Augustin Yapo, Paule‐Denise Kondo, Aya Liliane Touré, Walamitien Cyrille Edé, Kotchi Fabrice Dah, Cyrille Serges Bogui, Pascal Physiol Rep Original Articles BACKGROUND: Some previous works have focused on dose‐response relationship between cocoa consumption and blood pressure in Caucasians. As black subjects have lower nitric oxide bioavailability, the aim of this work was to determine the dose‐effect relation between cocoa and blood pressure in black Africans. METHOD: One hundred and thirty healthy black African males aged 18–30 were randomly assigned into four groups: three groups consuming 10 g, 5 g, or 2 g of cocoa powder daily for three weeks and one control group that did not consume cocoa. Systolic blood pressure (SBP), diastolic blood pressure (DBP), and heart rate (HR) were measured on day 1 (D1, before any subject consumed cocoa), D8, D15, and D22. Means of the parameters at each of the four visits and changes of the means were compared among the groups. RESULTS: Significant decrease in SBP was noted in consumers of 10 g compared to controls in the 1st week, and compared to consumers of 2 g in the 2nd and 3rd weeks of follow‐up. Means and changes of DBP were statistically similar among the four groups. CONCLUSION: Among our cohort, decrease in SBP was significantly greater in the heavy cocoa consumer group (10 g) compared to the low consumer group (2 g), but there was no statistically significant difference when compared with the intermediate consumer group (5 g). The dose‐response relationship between cocoa consumption and changes in SBP was not linear. No relationship was found between cocoa consumption and DBP. John Wiley and Sons Inc. 2021-10-21 /pmc/articles/PMC8531838/ /pubmed/34676690 http://dx.doi.org/10.14814/phy2.15070 Text en © 2021 The Authors. Physiological Reports published by Wiley Periodicals LLC on behalf of The Physiological Society and the American Physiological Society https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Articles
Balayssac‐Siransy, Edwige
Ouattara, Soualiho
Boka, Kotchi Joël Michée
Ahiboh, Hugues
Yéo, Téniloh Augustin
Yapo, Paule‐Denise
Kondo, Aya Liliane
Touré, Walamitien Cyrille
Edé, Kotchi Fabrice
Dah, Cyrille Serges
Bogui, Pascal
Dose‐effect relation between regular consumption of 100% cocoa powder and blood pressure in young, healthy black Africans
title Dose‐effect relation between regular consumption of 100% cocoa powder and blood pressure in young, healthy black Africans
title_full Dose‐effect relation between regular consumption of 100% cocoa powder and blood pressure in young, healthy black Africans
title_fullStr Dose‐effect relation between regular consumption of 100% cocoa powder and blood pressure in young, healthy black Africans
title_full_unstemmed Dose‐effect relation between regular consumption of 100% cocoa powder and blood pressure in young, healthy black Africans
title_short Dose‐effect relation between regular consumption of 100% cocoa powder and blood pressure in young, healthy black Africans
title_sort dose‐effect relation between regular consumption of 100% cocoa powder and blood pressure in young, healthy black africans
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8531838/
https://www.ncbi.nlm.nih.gov/pubmed/34676690
http://dx.doi.org/10.14814/phy2.15070
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