Cargando…
Dose‐effect relation between regular consumption of 100% cocoa powder and blood pressure in young, healthy black Africans
BACKGROUND: Some previous works have focused on dose‐response relationship between cocoa consumption and blood pressure in Caucasians. As black subjects have lower nitric oxide bioavailability, the aim of this work was to determine the dose‐effect relation between cocoa and blood pressure in black A...
Autores principales: | , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8531838/ https://www.ncbi.nlm.nih.gov/pubmed/34676690 http://dx.doi.org/10.14814/phy2.15070 |
_version_ | 1784586949322866688 |
---|---|
author | Balayssac‐Siransy, Edwige Ouattara, Soualiho Boka, Kotchi Joël Michée Ahiboh, Hugues Yéo, Téniloh Augustin Yapo, Paule‐Denise Kondo, Aya Liliane Touré, Walamitien Cyrille Edé, Kotchi Fabrice Dah, Cyrille Serges Bogui, Pascal |
author_facet | Balayssac‐Siransy, Edwige Ouattara, Soualiho Boka, Kotchi Joël Michée Ahiboh, Hugues Yéo, Téniloh Augustin Yapo, Paule‐Denise Kondo, Aya Liliane Touré, Walamitien Cyrille Edé, Kotchi Fabrice Dah, Cyrille Serges Bogui, Pascal |
author_sort | Balayssac‐Siransy, Edwige |
collection | PubMed |
description | BACKGROUND: Some previous works have focused on dose‐response relationship between cocoa consumption and blood pressure in Caucasians. As black subjects have lower nitric oxide bioavailability, the aim of this work was to determine the dose‐effect relation between cocoa and blood pressure in black Africans. METHOD: One hundred and thirty healthy black African males aged 18–30 were randomly assigned into four groups: three groups consuming 10 g, 5 g, or 2 g of cocoa powder daily for three weeks and one control group that did not consume cocoa. Systolic blood pressure (SBP), diastolic blood pressure (DBP), and heart rate (HR) were measured on day 1 (D1, before any subject consumed cocoa), D8, D15, and D22. Means of the parameters at each of the four visits and changes of the means were compared among the groups. RESULTS: Significant decrease in SBP was noted in consumers of 10 g compared to controls in the 1st week, and compared to consumers of 2 g in the 2nd and 3rd weeks of follow‐up. Means and changes of DBP were statistically similar among the four groups. CONCLUSION: Among our cohort, decrease in SBP was significantly greater in the heavy cocoa consumer group (10 g) compared to the low consumer group (2 g), but there was no statistically significant difference when compared with the intermediate consumer group (5 g). The dose‐response relationship between cocoa consumption and changes in SBP was not linear. No relationship was found between cocoa consumption and DBP. |
format | Online Article Text |
id | pubmed-8531838 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-85318382021-10-28 Dose‐effect relation between regular consumption of 100% cocoa powder and blood pressure in young, healthy black Africans Balayssac‐Siransy, Edwige Ouattara, Soualiho Boka, Kotchi Joël Michée Ahiboh, Hugues Yéo, Téniloh Augustin Yapo, Paule‐Denise Kondo, Aya Liliane Touré, Walamitien Cyrille Edé, Kotchi Fabrice Dah, Cyrille Serges Bogui, Pascal Physiol Rep Original Articles BACKGROUND: Some previous works have focused on dose‐response relationship between cocoa consumption and blood pressure in Caucasians. As black subjects have lower nitric oxide bioavailability, the aim of this work was to determine the dose‐effect relation between cocoa and blood pressure in black Africans. METHOD: One hundred and thirty healthy black African males aged 18–30 were randomly assigned into four groups: three groups consuming 10 g, 5 g, or 2 g of cocoa powder daily for three weeks and one control group that did not consume cocoa. Systolic blood pressure (SBP), diastolic blood pressure (DBP), and heart rate (HR) were measured on day 1 (D1, before any subject consumed cocoa), D8, D15, and D22. Means of the parameters at each of the four visits and changes of the means were compared among the groups. RESULTS: Significant decrease in SBP was noted in consumers of 10 g compared to controls in the 1st week, and compared to consumers of 2 g in the 2nd and 3rd weeks of follow‐up. Means and changes of DBP were statistically similar among the four groups. CONCLUSION: Among our cohort, decrease in SBP was significantly greater in the heavy cocoa consumer group (10 g) compared to the low consumer group (2 g), but there was no statistically significant difference when compared with the intermediate consumer group (5 g). The dose‐response relationship between cocoa consumption and changes in SBP was not linear. No relationship was found between cocoa consumption and DBP. John Wiley and Sons Inc. 2021-10-21 /pmc/articles/PMC8531838/ /pubmed/34676690 http://dx.doi.org/10.14814/phy2.15070 Text en © 2021 The Authors. Physiological Reports published by Wiley Periodicals LLC on behalf of The Physiological Society and the American Physiological Society https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Articles Balayssac‐Siransy, Edwige Ouattara, Soualiho Boka, Kotchi Joël Michée Ahiboh, Hugues Yéo, Téniloh Augustin Yapo, Paule‐Denise Kondo, Aya Liliane Touré, Walamitien Cyrille Edé, Kotchi Fabrice Dah, Cyrille Serges Bogui, Pascal Dose‐effect relation between regular consumption of 100% cocoa powder and blood pressure in young, healthy black Africans |
title | Dose‐effect relation between regular consumption of 100% cocoa powder and blood pressure in young, healthy black Africans |
title_full | Dose‐effect relation between regular consumption of 100% cocoa powder and blood pressure in young, healthy black Africans |
title_fullStr | Dose‐effect relation between regular consumption of 100% cocoa powder and blood pressure in young, healthy black Africans |
title_full_unstemmed | Dose‐effect relation between regular consumption of 100% cocoa powder and blood pressure in young, healthy black Africans |
title_short | Dose‐effect relation between regular consumption of 100% cocoa powder and blood pressure in young, healthy black Africans |
title_sort | dose‐effect relation between regular consumption of 100% cocoa powder and blood pressure in young, healthy black africans |
topic | Original Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8531838/ https://www.ncbi.nlm.nih.gov/pubmed/34676690 http://dx.doi.org/10.14814/phy2.15070 |
work_keys_str_mv | AT balayssacsiransyedwige doseeffectrelationbetweenregularconsumptionof100cocoapowderandbloodpressureinyounghealthyblackafricans AT ouattarasoualiho doseeffectrelationbetweenregularconsumptionof100cocoapowderandbloodpressureinyounghealthyblackafricans AT bokakotchijoelmichee doseeffectrelationbetweenregularconsumptionof100cocoapowderandbloodpressureinyounghealthyblackafricans AT ahibohhugues doseeffectrelationbetweenregularconsumptionof100cocoapowderandbloodpressureinyounghealthyblackafricans AT yeotenilohaugustin doseeffectrelationbetweenregularconsumptionof100cocoapowderandbloodpressureinyounghealthyblackafricans AT yapopauledenise doseeffectrelationbetweenregularconsumptionof100cocoapowderandbloodpressureinyounghealthyblackafricans AT kondoayaliliane doseeffectrelationbetweenregularconsumptionof100cocoapowderandbloodpressureinyounghealthyblackafricans AT tourewalamitiencyrille doseeffectrelationbetweenregularconsumptionof100cocoapowderandbloodpressureinyounghealthyblackafricans AT edekotchifabrice doseeffectrelationbetweenregularconsumptionof100cocoapowderandbloodpressureinyounghealthyblackafricans AT dahcyrilleserges doseeffectrelationbetweenregularconsumptionof100cocoapowderandbloodpressureinyounghealthyblackafricans AT boguipascal doseeffectrelationbetweenregularconsumptionof100cocoapowderandbloodpressureinyounghealthyblackafricans |