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CON: Procalcitonin does not have clinical utility in children with community-acquired pneumonia
Most clinical studies supporting procalcitonin (PCT)-guided management of lower respiratory tract infections have been performed in adults. There is a paucity of studies evaluating the clinical impact of PCT use in children and limited data informing age-appropriate PCT cut-offs; diagnostic accuracy...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8531866/ https://www.ncbi.nlm.nih.gov/pubmed/34704032 http://dx.doi.org/10.1093/jacamr/dlab152 |
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author | Banerjee, Ritu |
author_facet | Banerjee, Ritu |
author_sort | Banerjee, Ritu |
collection | PubMed |
description | Most clinical studies supporting procalcitonin (PCT)-guided management of lower respiratory tract infections have been performed in adults. There is a paucity of studies evaluating the clinical impact of PCT use in children and limited data informing age-appropriate PCT cut-offs; diagnostic accuracy in immunocompromised children; patient subgroups most likely to benefit from PCT testing; whether PCT adds value beyond available rapid molecular viral diagnostics; and optimal implementation strategies for PCT-guided treatment. At the present time there is little evidence to support routine use of PCT to aid management of paediatric pneumonia. |
format | Online Article Text |
id | pubmed-8531866 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-85318662021-10-25 CON: Procalcitonin does not have clinical utility in children with community-acquired pneumonia Banerjee, Ritu JAC Antimicrob Resist For Debate Most clinical studies supporting procalcitonin (PCT)-guided management of lower respiratory tract infections have been performed in adults. There is a paucity of studies evaluating the clinical impact of PCT use in children and limited data informing age-appropriate PCT cut-offs; diagnostic accuracy in immunocompromised children; patient subgroups most likely to benefit from PCT testing; whether PCT adds value beyond available rapid molecular viral diagnostics; and optimal implementation strategies for PCT-guided treatment. At the present time there is little evidence to support routine use of PCT to aid management of paediatric pneumonia. Oxford University Press 2021-10-22 /pmc/articles/PMC8531866/ /pubmed/34704032 http://dx.doi.org/10.1093/jacamr/dlab152 Text en © The Author(s) 2021. Published by Oxford University Press on behalf of the British Society for Antimicrobial Chemotherapy. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | For Debate Banerjee, Ritu CON: Procalcitonin does not have clinical utility in children with community-acquired pneumonia |
title | CON: Procalcitonin does not have clinical utility in children with community-acquired pneumonia |
title_full | CON: Procalcitonin does not have clinical utility in children with community-acquired pneumonia |
title_fullStr | CON: Procalcitonin does not have clinical utility in children with community-acquired pneumonia |
title_full_unstemmed | CON: Procalcitonin does not have clinical utility in children with community-acquired pneumonia |
title_short | CON: Procalcitonin does not have clinical utility in children with community-acquired pneumonia |
title_sort | con: procalcitonin does not have clinical utility in children with community-acquired pneumonia |
topic | For Debate |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8531866/ https://www.ncbi.nlm.nih.gov/pubmed/34704032 http://dx.doi.org/10.1093/jacamr/dlab152 |
work_keys_str_mv | AT banerjeeritu conprocalcitonindoesnothaveclinicalutilityinchildrenwithcommunityacquiredpneumonia |