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CON: Procalcitonin does not have clinical utility in children with community-acquired pneumonia

Most clinical studies supporting procalcitonin (PCT)-guided management of lower respiratory tract infections have been performed in adults. There is a paucity of studies evaluating the clinical impact of PCT use in children and limited data informing age-appropriate PCT cut-offs; diagnostic accuracy...

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Detalles Bibliográficos
Autor principal: Banerjee, Ritu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8531866/
https://www.ncbi.nlm.nih.gov/pubmed/34704032
http://dx.doi.org/10.1093/jacamr/dlab152
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author Banerjee, Ritu
author_facet Banerjee, Ritu
author_sort Banerjee, Ritu
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description Most clinical studies supporting procalcitonin (PCT)-guided management of lower respiratory tract infections have been performed in adults. There is a paucity of studies evaluating the clinical impact of PCT use in children and limited data informing age-appropriate PCT cut-offs; diagnostic accuracy in immunocompromised children; patient subgroups most likely to benefit from PCT testing; whether PCT adds value beyond available rapid molecular viral diagnostics; and optimal implementation strategies for PCT-guided treatment. At the present time there is little evidence to support routine use of PCT to aid management of paediatric pneumonia.
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spelling pubmed-85318662021-10-25 CON: Procalcitonin does not have clinical utility in children with community-acquired pneumonia Banerjee, Ritu JAC Antimicrob Resist For Debate Most clinical studies supporting procalcitonin (PCT)-guided management of lower respiratory tract infections have been performed in adults. There is a paucity of studies evaluating the clinical impact of PCT use in children and limited data informing age-appropriate PCT cut-offs; diagnostic accuracy in immunocompromised children; patient subgroups most likely to benefit from PCT testing; whether PCT adds value beyond available rapid molecular viral diagnostics; and optimal implementation strategies for PCT-guided treatment. At the present time there is little evidence to support routine use of PCT to aid management of paediatric pneumonia. Oxford University Press 2021-10-22 /pmc/articles/PMC8531866/ /pubmed/34704032 http://dx.doi.org/10.1093/jacamr/dlab152 Text en © The Author(s) 2021. Published by Oxford University Press on behalf of the British Society for Antimicrobial Chemotherapy. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle For Debate
Banerjee, Ritu
CON: Procalcitonin does not have clinical utility in children with community-acquired pneumonia
title CON: Procalcitonin does not have clinical utility in children with community-acquired pneumonia
title_full CON: Procalcitonin does not have clinical utility in children with community-acquired pneumonia
title_fullStr CON: Procalcitonin does not have clinical utility in children with community-acquired pneumonia
title_full_unstemmed CON: Procalcitonin does not have clinical utility in children with community-acquired pneumonia
title_short CON: Procalcitonin does not have clinical utility in children with community-acquired pneumonia
title_sort con: procalcitonin does not have clinical utility in children with community-acquired pneumonia
topic For Debate
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8531866/
https://www.ncbi.nlm.nih.gov/pubmed/34704032
http://dx.doi.org/10.1093/jacamr/dlab152
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