PIR-B Regulates CD4(+) IL17a(+) T-Cell Survival and Restricts T-Cell–Dependent Intestinal Inflammatory Responses

BACKGROUND & AIMS: CD4(+) T cells are regulated by activating and inhibitory cues, and dysregulation of these proper regulatory inputs predisposes these cells to aberrant inflammation and exacerbation of disease. We investigated the role of the inhibitory receptor paired immunoglobulin-like rece...

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Detalles Bibliográficos
Autores principales: Uddin, Jazib, Tomar, Sunil, Sharma, Ankit, Waggoner, Lisa, Ganesan, Varsha, Marella, Sahiti, Yang, Yanfen, Noah, Taeko, Vanoni, Simone, Patterson, Andrew, Zeng, Chang, Foster, Paul S., Newberry, Rodney, Bishu, Shrinivas, Kao, John Y., Rosen, Michael J., Denson, Lee, King, Philip D., Hoebe, Kasper, Divanovic, Senad, Munitz, Ariel, Hogan, Simon P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8531983/
https://www.ncbi.nlm.nih.gov/pubmed/34242819
http://dx.doi.org/10.1016/j.jcmgh.2021.06.013

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