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Puerarin alleviates the ototoxicity of gentamicin by inhibiting the mitochondria-dependent apoptosis pathway

Gentamicin (GM) is a commonly used antibiotic, and ototoxicity is one of its side effects. Puerarin (PU) is an isoflavone in kudzu roots that exerts a number of pharmacological effects, including antioxidative and free radical scavenging effects. The present study investigated whether PU could prote...

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Detalles Bibliográficos
Autores principales: Niu, Ping, Sun, Yuxuan, Wang, Shiyi, Li, Guang, Tang, Xiaomin, Sun, Jiaqiang, Pan, Chunchen, Sun, Jingwu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8532108/
https://www.ncbi.nlm.nih.gov/pubmed/34651662
http://dx.doi.org/10.3892/mmr.2021.12491