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Chemogenetic stimulation of the G(i) pathway in astrocytes suppresses neuroinflammation

Engineered G protein‐coupled receptors (GPCRs) are commonly used in chemogenetics as designer receptors exclusively activated by designer drugs (DREADDs). Although several GPCRs have been studied in astrocytes using a chemogenetic approach, the functional role of the astrocytic G(i) pathway is not c...

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Detalles Bibliográficos
Autores principales: Kim, Jae‐Hong, Rahman, Md Habibur, Lee, Won Ha, Suk, Kyoungho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8532135/
https://www.ncbi.nlm.nih.gov/pubmed/34676988
http://dx.doi.org/10.1002/prp2.822