Activated natural killer cells predict poor clinical prognosis in high-risk B- and T-cell acute lymphoblastic leukemia

B- and T-cell acute lymphoblastic leukemia (B/T-ALL) may be refractory or recur after therapy by suppressing host anticancer immune surveillance mediated specifically by natural killer (NK) cells. We delineated the phenotypic and functional defects in NK cells from high-risk patients with B/T-ALL us...

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Detalles Bibliográficos
Autores principales: Duault, Caroline, Kumar, Anil, Taghi Khani, Adeleh, Lee, Sung June, Yang, Lu, Huang, Min, Hurtz, Christian, Manning, Bryan, Ghoda, Lucy, McDonald, Tinisha, Lacayo, Norman J., Sakamoto, Kathleen M., Carroll, Martin, Tasian, Sarah K., Marcucci, Guido, Yu, Jianhua, Caligiuri, Michael A., Maecker, Holden T., Swaminathan, Srividya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Hematology 2021
Materias:
Lymphoid Neoplasia
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8532198/
https://www.ncbi.nlm.nih.gov/pubmed/34077953
http://dx.doi.org/10.1182/blood.2020009871

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