Extensive Longitudinal Transverse Myelitis Associated With CSF Epstein-Barr Virus Infection: A Case Report

Background. Acute transverse myelitis (ATM) in children can be secondary to central nervous system infections. Several reports have associated ATM with Epstein-Barr virus (EBV) infection. Case presentation. We report a previously healthy 10-year-old boy with paraparesis that started 7 days before ad...

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Detalles Bibliográficos
Autores principales: Singhi, Pratibha, Sharma, Jai Prakash, Gautam, Rakchhya, Indra, Raden M., Rafli, Achmad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2021
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8532220/
https://www.ncbi.nlm.nih.gov/pubmed/34692894
http://dx.doi.org/10.1177/2329048X211049958
Descripción
Sumario:Background. Acute transverse myelitis (ATM) in children can be secondary to central nervous system infections. Several reports have associated ATM with Epstein-Barr virus (EBV) infection. Case presentation. We report a previously healthy 10-year-old boy with paraparesis that started 7 days before admission. Spinal T2W MRI revealed extensive hyperintense lesions. Cerebrospinal fluid WBC was 268/µL and PCR examination was positive for EBV. High dose methylprednisolone (1 g/kg) was given for 5 days, the child was symptom free 3 months after presentation. Conclusion. Epstein-Barr infection should be considered in ATM, particularly when CSF WBC count is high.

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