Extensive Longitudinal Transverse Myelitis Associated With CSF Epstein-Barr Virus Infection: A Case Report

Background. Acute transverse myelitis (ATM) in children can be secondary to central nervous system infections. Several reports have associated ATM with Epstein-Barr virus (EBV) infection. Case presentation. We report a previously healthy 10-year-old boy with paraparesis that started 7 days before ad...

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Autores principales: Singhi, Pratibha, Sharma, Jai Prakash, Gautam, Rakchhya, Indra, Raden M., Rafli, Achmad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2021
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8532220/
https://www.ncbi.nlm.nih.gov/pubmed/34692894
http://dx.doi.org/10.1177/2329048X211049958
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author Singhi, Pratibha
Sharma, Jai Prakash
Gautam, Rakchhya
Indra, Raden M.
Rafli, Achmad
author_facet Singhi, Pratibha
Sharma, Jai Prakash
Gautam, Rakchhya
Indra, Raden M.
Rafli, Achmad
author_sort Singhi, Pratibha
collection PubMed
description Background. Acute transverse myelitis (ATM) in children can be secondary to central nervous system infections. Several reports have associated ATM with Epstein-Barr virus (EBV) infection. Case presentation. We report a previously healthy 10-year-old boy with paraparesis that started 7 days before admission. Spinal T2W MRI revealed extensive hyperintense lesions. Cerebrospinal fluid WBC was 268/µL and PCR examination was positive for EBV. High dose methylprednisolone (1 g/kg) was given for 5 days, the child was symptom free 3 months after presentation. Conclusion. Epstein-Barr infection should be considered in ATM, particularly when CSF WBC count is high.
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spelling pubmed-85322202021-10-23 Extensive Longitudinal Transverse Myelitis Associated With CSF Epstein-Barr Virus Infection: A Case Report Singhi, Pratibha Sharma, Jai Prakash Gautam, Rakchhya Indra, Raden M. Rafli, Achmad Child Neurol Open Case Report Background. Acute transverse myelitis (ATM) in children can be secondary to central nervous system infections. Several reports have associated ATM with Epstein-Barr virus (EBV) infection. Case presentation. We report a previously healthy 10-year-old boy with paraparesis that started 7 days before admission. Spinal T2W MRI revealed extensive hyperintense lesions. Cerebrospinal fluid WBC was 268/µL and PCR examination was positive for EBV. High dose methylprednisolone (1 g/kg) was given for 5 days, the child was symptom free 3 months after presentation. Conclusion. Epstein-Barr infection should be considered in ATM, particularly when CSF WBC count is high. SAGE Publications 2021-10-20 /pmc/articles/PMC8532220/ /pubmed/34692894 http://dx.doi.org/10.1177/2329048X211049958 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by-nc/4.0/This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Case Report
Singhi, Pratibha
Sharma, Jai Prakash
Gautam, Rakchhya
Indra, Raden M.
Rafli, Achmad
Extensive Longitudinal Transverse Myelitis Associated With CSF Epstein-Barr Virus Infection: A Case Report
title Extensive Longitudinal Transverse Myelitis Associated With CSF Epstein-Barr Virus Infection: A Case Report
title_full Extensive Longitudinal Transverse Myelitis Associated With CSF Epstein-Barr Virus Infection: A Case Report
title_fullStr Extensive Longitudinal Transverse Myelitis Associated With CSF Epstein-Barr Virus Infection: A Case Report
title_full_unstemmed Extensive Longitudinal Transverse Myelitis Associated With CSF Epstein-Barr Virus Infection: A Case Report
title_short Extensive Longitudinal Transverse Myelitis Associated With CSF Epstein-Barr Virus Infection: A Case Report
title_sort extensive longitudinal transverse myelitis associated with csf epstein-barr virus infection: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8532220/
https://www.ncbi.nlm.nih.gov/pubmed/34692894
http://dx.doi.org/10.1177/2329048X211049958
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