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Factors influencing the occurrence of electrolyte disorders in cancer patients

OBJECTIVE: The objective of this study was to determine the magnitude of electrolyte disorders and influencing factors among cancer patients in Southwest Ethiopia. METHODS: Facility-based cross-sectional study was conducted in Jimma Medical Center (JMC). Eighty-four cancer patients admitted to JMC w...

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Autores principales: Alem, Addis, Edae, Chala Kenenisa, Kelta Wabalo, Endriyas, Abera Tareke, Amare, Ayalew Bedanie, Almaz, Reta, Wondu, Bariso, Moyeta, Bekele, Gadisa, Zawdie, Belay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8532243/
https://www.ncbi.nlm.nih.gov/pubmed/34691474
http://dx.doi.org/10.1177/20503121211052861
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author Alem, Addis
Edae, Chala Kenenisa
Kelta Wabalo, Endriyas
Abera Tareke, Amare
Ayalew Bedanie, Almaz
Reta, Wondu
Bariso, Moyeta
Bekele, Gadisa
Zawdie, Belay
author_facet Alem, Addis
Edae, Chala Kenenisa
Kelta Wabalo, Endriyas
Abera Tareke, Amare
Ayalew Bedanie, Almaz
Reta, Wondu
Bariso, Moyeta
Bekele, Gadisa
Zawdie, Belay
author_sort Alem, Addis
collection PubMed
description OBJECTIVE: The objective of this study was to determine the magnitude of electrolyte disorders and influencing factors among cancer patients in Southwest Ethiopia. METHODS: Facility-based cross-sectional study was conducted in Jimma Medical Center (JMC). Eighty-four cancer patients admitted to JMC were recruited for this study. A structured questionnaire and serum electrolyte measurements were used for data collection. Bivariate and multiple logistic regression was employed to determine the association between electrolyte disorders and associated factors among admitted cancer patients. P value ⩽ 0.05 was used as a cut point to declare statistical significance. RESULT: The overall prevalence of electrolyte disorders was 60.7%. The presence or absence of comorbid diseases, age, body mass index (BMI), nutritional status, and current prescribed medication use were associated with electrolyte disorders. Younger patients had lower odds for electrolyte disorders (odds ratio (OR) = 0.128 (P value = 0.05) and OR = 0.08 (P value = 0.033)) for the first and the second quartile, respectively. Underweight patients had a threefold likelihood to develop electrolyte disorders (OR = 3.13 (P value = 0.043)) than having normal BMI. Compared with those in need of nutritional intervention, patients not in need of nutritional intervention had lower odds for the disorders (OR = 0.109 (P value = 0.006)). Medication had increased the likelihood of electrolyte disorders by 5.5 times than with no medication (P value = 0.023). Those who had comorbid disease had 10 times likely to develop electrolyte disorders than those who did not have comorbid diseases (P value = 0.004). CONCLUSION: Electrolyte disorders were prevalent in cancer patients. Age, BMI, nutritional condition, comorbid disease, and prescribed drugs were the predictors of electrolyte disorders in cancer patients. Authors recommend routine screening of electrolyte disorders in cancer patients and special emphasis on controlling and managing risk factors.
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spelling pubmed-85322432021-10-23 Factors influencing the occurrence of electrolyte disorders in cancer patients Alem, Addis Edae, Chala Kenenisa Kelta Wabalo, Endriyas Abera Tareke, Amare Ayalew Bedanie, Almaz Reta, Wondu Bariso, Moyeta Bekele, Gadisa Zawdie, Belay SAGE Open Med Original Research Article OBJECTIVE: The objective of this study was to determine the magnitude of electrolyte disorders and influencing factors among cancer patients in Southwest Ethiopia. METHODS: Facility-based cross-sectional study was conducted in Jimma Medical Center (JMC). Eighty-four cancer patients admitted to JMC were recruited for this study. A structured questionnaire and serum electrolyte measurements were used for data collection. Bivariate and multiple logistic regression was employed to determine the association between electrolyte disorders and associated factors among admitted cancer patients. P value ⩽ 0.05 was used as a cut point to declare statistical significance. RESULT: The overall prevalence of electrolyte disorders was 60.7%. The presence or absence of comorbid diseases, age, body mass index (BMI), nutritional status, and current prescribed medication use were associated with electrolyte disorders. Younger patients had lower odds for electrolyte disorders (odds ratio (OR) = 0.128 (P value = 0.05) and OR = 0.08 (P value = 0.033)) for the first and the second quartile, respectively. Underweight patients had a threefold likelihood to develop electrolyte disorders (OR = 3.13 (P value = 0.043)) than having normal BMI. Compared with those in need of nutritional intervention, patients not in need of nutritional intervention had lower odds for the disorders (OR = 0.109 (P value = 0.006)). Medication had increased the likelihood of electrolyte disorders by 5.5 times than with no medication (P value = 0.023). Those who had comorbid disease had 10 times likely to develop electrolyte disorders than those who did not have comorbid diseases (P value = 0.004). CONCLUSION: Electrolyte disorders were prevalent in cancer patients. Age, BMI, nutritional condition, comorbid disease, and prescribed drugs were the predictors of electrolyte disorders in cancer patients. Authors recommend routine screening of electrolyte disorders in cancer patients and special emphasis on controlling and managing risk factors. SAGE Publications 2021-10-20 /pmc/articles/PMC8532243/ /pubmed/34691474 http://dx.doi.org/10.1177/20503121211052861 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by-nc/4.0/This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Original Research Article
Alem, Addis
Edae, Chala Kenenisa
Kelta Wabalo, Endriyas
Abera Tareke, Amare
Ayalew Bedanie, Almaz
Reta, Wondu
Bariso, Moyeta
Bekele, Gadisa
Zawdie, Belay
Factors influencing the occurrence of electrolyte disorders in cancer patients
title Factors influencing the occurrence of electrolyte disorders in cancer patients
title_full Factors influencing the occurrence of electrolyte disorders in cancer patients
title_fullStr Factors influencing the occurrence of electrolyte disorders in cancer patients
title_full_unstemmed Factors influencing the occurrence of electrolyte disorders in cancer patients
title_short Factors influencing the occurrence of electrolyte disorders in cancer patients
title_sort factors influencing the occurrence of electrolyte disorders in cancer patients
topic Original Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8532243/
https://www.ncbi.nlm.nih.gov/pubmed/34691474
http://dx.doi.org/10.1177/20503121211052861
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