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Induced pluripotent stem cells can improve thrombolytic effect of low-dose rt-PA after acute carotid thrombosis in rat
BACKGROUND: Intravenous thrombolysis using recombinant tissue plasminogen activator (rt-PA) is the standard treatment for acute ischemic stroke. Standard-dose rt-PA (0.9 mg/kg) is known to achieve good recanalization but carries a high bleeding risk. Lower dose of rt-PA has less bleeding risk but ca...
Autores principales: | Hsieh, Hsi-Lung, Liang, Ching-Chung, Lu, Cheng-You, Yang, Jen-Tsung, Chung, Chiu-Yen, Ko, Yu-Shien, Lee, Tsong-Hai |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8532293/ https://www.ncbi.nlm.nih.gov/pubmed/34674761 http://dx.doi.org/10.1186/s13287-021-02615-z |
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