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Employment of patients with kidney failure treated with dialysis or kidney transplantation—a systematic review and meta-analysis
BACKGROUND: Patients with kidney failure treated with dialysis or kidney transplantation experience difficulties maintaining employment due to the condition itself and the treatment. We aimed to establish the rate of employment before and after initiation of dialysis and kidney transplantation and t...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8532382/ https://www.ncbi.nlm.nih.gov/pubmed/34686138 http://dx.doi.org/10.1186/s12882-021-02552-2 |
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author | Kirkeskov, Lilli Carlsen, Rasmus K. Lund, Thomas Buus, Niels Henrik |
author_facet | Kirkeskov, Lilli Carlsen, Rasmus K. Lund, Thomas Buus, Niels Henrik |
author_sort | Kirkeskov, Lilli |
collection | PubMed |
description | BACKGROUND: Patients with kidney failure treated with dialysis or kidney transplantation experience difficulties maintaining employment due to the condition itself and the treatment. We aimed to establish the rate of employment before and after initiation of dialysis and kidney transplantation and to identify predictors of employment during dialysis and posttransplant. METHODS: This systematic review and meta-analysis were carried out according to the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guidelines for studies that included employment rate in adults receiving dialysis or a kidney transplant. The literature search included cross-sectional or cohort studies published in English between January 1966 and August 2020 in the PubMed, Embase, and Cochrane Library databases. Data on employment rate, study population, age, gender, educational level, dialysis duration, kidney donor, ethnicity, dialysis modality, waiting time for transplantation, diabetes, and depression were extracted. Quality assessment was performed using the Newcastle–Ottawa Scale. Meta-analysis for predictors for employment, with odds ratios and confidence intervals, and tests for heterogeneity, using chi-square and I(2) statistics, were calculated. PROSPERO registration number: CRD42020188853. RESULTS: Thirty-three studies included 162,059 participants receiving dialysis, and 31 studies included 137,742 participants who received kidney transplantation. Dialysis patients were on average 52.6 years old (range: 16–79; 60.3% male), and kidney transplant patients were 46.7 years old (range: 18–78; 59.8% male). The employment rate (weighted mean) for dialysis patients was 26.3% (range: 10.5–59.7%); the employment rate was 36.9% pretransplant (range: 25–86%) and 38.2% posttransplant (range: 14.2–85%). Predictors for employment during dialysis and posttransplant were male, gender, age, being without diabetes, peritoneal dialysis, and higher educational level, and predictors of posttransplant: pretransplant employment included transplantation with a living donor kidney, and being without depression. CONCLUSIONS: Patients with kidney failure had a low employment rate during dialysis and pre- and posttransplant. Kidney failure patients should be supported through a combination of clinical and social measures to ensure that they remain working. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12882-021-02552-2. |
format | Online Article Text |
id | pubmed-8532382 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-85323822021-10-25 Employment of patients with kidney failure treated with dialysis or kidney transplantation—a systematic review and meta-analysis Kirkeskov, Lilli Carlsen, Rasmus K. Lund, Thomas Buus, Niels Henrik BMC Nephrol Research BACKGROUND: Patients with kidney failure treated with dialysis or kidney transplantation experience difficulties maintaining employment due to the condition itself and the treatment. We aimed to establish the rate of employment before and after initiation of dialysis and kidney transplantation and to identify predictors of employment during dialysis and posttransplant. METHODS: This systematic review and meta-analysis were carried out according to the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guidelines for studies that included employment rate in adults receiving dialysis or a kidney transplant. The literature search included cross-sectional or cohort studies published in English between January 1966 and August 2020 in the PubMed, Embase, and Cochrane Library databases. Data on employment rate, study population, age, gender, educational level, dialysis duration, kidney donor, ethnicity, dialysis modality, waiting time for transplantation, diabetes, and depression were extracted. Quality assessment was performed using the Newcastle–Ottawa Scale. Meta-analysis for predictors for employment, with odds ratios and confidence intervals, and tests for heterogeneity, using chi-square and I(2) statistics, were calculated. PROSPERO registration number: CRD42020188853. RESULTS: Thirty-three studies included 162,059 participants receiving dialysis, and 31 studies included 137,742 participants who received kidney transplantation. Dialysis patients were on average 52.6 years old (range: 16–79; 60.3% male), and kidney transplant patients were 46.7 years old (range: 18–78; 59.8% male). The employment rate (weighted mean) for dialysis patients was 26.3% (range: 10.5–59.7%); the employment rate was 36.9% pretransplant (range: 25–86%) and 38.2% posttransplant (range: 14.2–85%). Predictors for employment during dialysis and posttransplant were male, gender, age, being without diabetes, peritoneal dialysis, and higher educational level, and predictors of posttransplant: pretransplant employment included transplantation with a living donor kidney, and being without depression. CONCLUSIONS: Patients with kidney failure had a low employment rate during dialysis and pre- and posttransplant. Kidney failure patients should be supported through a combination of clinical and social measures to ensure that they remain working. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12882-021-02552-2. BioMed Central 2021-10-22 /pmc/articles/PMC8532382/ /pubmed/34686138 http://dx.doi.org/10.1186/s12882-021-02552-2 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data. |
spellingShingle | Research Kirkeskov, Lilli Carlsen, Rasmus K. Lund, Thomas Buus, Niels Henrik Employment of patients with kidney failure treated with dialysis or kidney transplantation—a systematic review and meta-analysis |
title | Employment of patients with kidney failure treated with dialysis or kidney transplantation—a systematic review and meta-analysis |
title_full | Employment of patients with kidney failure treated with dialysis or kidney transplantation—a systematic review and meta-analysis |
title_fullStr | Employment of patients with kidney failure treated with dialysis or kidney transplantation—a systematic review and meta-analysis |
title_full_unstemmed | Employment of patients with kidney failure treated with dialysis or kidney transplantation—a systematic review and meta-analysis |
title_short | Employment of patients with kidney failure treated with dialysis or kidney transplantation—a systematic review and meta-analysis |
title_sort | employment of patients with kidney failure treated with dialysis or kidney transplantation—a systematic review and meta-analysis |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8532382/ https://www.ncbi.nlm.nih.gov/pubmed/34686138 http://dx.doi.org/10.1186/s12882-021-02552-2 |
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