ATG8ylation of proteins: A way to cope with cell stress?

The ATG8 family of proteins regulates autophagy in a variety of ways. Recently, ATG8s were demonstrated to conjugate directly to cellular proteins in a process termed “ATG8ylation,” which is amplified by mitochondrial damage and antagonized by ATG4 proteases. ATG8s may have an emerging role as small...

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Detalles Bibliográficos
Autores principales: Carosi, Julian M., Nguyen, Thanh N., Lazarou, Michael, Kumar, Sharad, Sargeant, Timothy J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Viewpoint
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8532562/
https://www.ncbi.nlm.nih.gov/pubmed/34671813
http://dx.doi.org/10.1083/jcb.202108120
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author Carosi, Julian M.
Nguyen, Thanh N.
Lazarou, Michael
Kumar, Sharad
Sargeant, Timothy J.
author_facet Carosi, Julian M.
Nguyen, Thanh N.
Lazarou, Michael
Kumar, Sharad
Sargeant, Timothy J.
author_sort Carosi, Julian M.
collection PubMed
description The ATG8 family of proteins regulates autophagy in a variety of ways. Recently, ATG8s were demonstrated to conjugate directly to cellular proteins in a process termed “ATG8ylation,” which is amplified by mitochondrial damage and antagonized by ATG4 proteases. ATG8s may have an emerging role as small protein modifiers.
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spelling pubmed-85325622022-05-01 ATG8ylation of proteins: A way to cope with cell stress? Carosi, Julian M. Nguyen, Thanh N. Lazarou, Michael Kumar, Sharad Sargeant, Timothy J. J Cell Biol Viewpoint The ATG8 family of proteins regulates autophagy in a variety of ways. Recently, ATG8s were demonstrated to conjugate directly to cellular proteins in a process termed “ATG8ylation,” which is amplified by mitochondrial damage and antagonized by ATG4 proteases. ATG8s may have an emerging role as small protein modifiers. Rockefeller University Press 2021-10-20 /pmc/articles/PMC8532562/ /pubmed/34671813 http://dx.doi.org/10.1083/jcb.202108120 Text en © 2021 Carosi et al. https://creativecommons.org/licenses/by-nc-sa/4.0/http://www.rupress.org/terms/This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms/). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 International license, as described at https://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Viewpoint
Carosi, Julian M.
Nguyen, Thanh N.
Lazarou, Michael
Kumar, Sharad
Sargeant, Timothy J.
ATG8ylation of proteins: A way to cope with cell stress?
title ATG8ylation of proteins: A way to cope with cell stress?
title_full ATG8ylation of proteins: A way to cope with cell stress?
title_fullStr ATG8ylation of proteins: A way to cope with cell stress?
title_full_unstemmed ATG8ylation of proteins: A way to cope with cell stress?
title_short ATG8ylation of proteins: A way to cope with cell stress?
title_sort atg8ylation of proteins: a way to cope with cell stress?
topic Viewpoint
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8532562/
https://www.ncbi.nlm.nih.gov/pubmed/34671813
http://dx.doi.org/10.1083/jcb.202108120
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