Surfaceome CRISPR screen identifies OLFML3 as a rhinovirus-inducible IFN antagonist

BACKGROUND: Rhinoviruses (RVs) cause more than half of common colds and, in some cases, more severe diseases. Functional genomics analyses of RVs using siRNA or genome-wide CRISPR screen uncovered a limited set of host factors, few of which have proven clinical relevance. RESULTS: Herein, we systema...

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Detalles Bibliográficos
Autores principales: Mei, Hong, Zha, Zhao, Wang, Wei, Xie, Yusang, Huang, Yuege, Li, Wenping, Wei, Dong, Zhang, Xinxin, Qu, Jieming, Liu, Jia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8532573/
https://www.ncbi.nlm.nih.gov/pubmed/34686207
http://dx.doi.org/10.1186/s13059-021-02513-w

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