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Ftsh Sensitizes Methicillin-Resistant Staphylococcus aureus to β-Lactam Antibiotics by Degrading YpfP, a Lipoteichoic Acid Synthesis Enzyme

In the Gram-positive pathogen Staphylococcus aureus, FtsH, a membrane-bound metalloprotease, plays a critical role in bacterial virulence and stress resistance. This protease is also known to sensitize methicillin-resistant Staphylococcus aureus (MRSA) to β-lactam antibiotics; however, the molecular...

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Detalles Bibliográficos
Autores principales: Yeo, Won-Sik, Jeong, Bohyun, Ullah, Nimat, Shah, Majid Ali, Ali, Amjad, Kim, Kyeong Kyu, Bae, Taeok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8532640/
https://www.ncbi.nlm.nih.gov/pubmed/34680778
http://dx.doi.org/10.3390/antibiotics10101198