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Ftsh Sensitizes Methicillin-Resistant Staphylococcus aureus to β-Lactam Antibiotics by Degrading YpfP, a Lipoteichoic Acid Synthesis Enzyme
In the Gram-positive pathogen Staphylococcus aureus, FtsH, a membrane-bound metalloprotease, plays a critical role in bacterial virulence and stress resistance. This protease is also known to sensitize methicillin-resistant Staphylococcus aureus (MRSA) to β-lactam antibiotics; however, the molecular...
Autores principales: | Yeo, Won-Sik, Jeong, Bohyun, Ullah, Nimat, Shah, Majid Ali, Ali, Amjad, Kim, Kyeong Kyu, Bae, Taeok |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8532640/ https://www.ncbi.nlm.nih.gov/pubmed/34680778 http://dx.doi.org/10.3390/antibiotics10101198 |
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