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Paralemnolins X and Y, New Antimicrobial Sesquiterpenoids from the Soft Coral Paralemnalia thyrsoide
The organic extracts of the Red Sea soft coral Paralemnalia thyrsoides has led to the identification of two neolemnane-type sesquiterpenoids: paralemnolins X and Y (1, 2). In addition to these newly characterized compounds, ten known metabolites (3–12) were isolated. Previously reported compounds we...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8532672/ https://www.ncbi.nlm.nih.gov/pubmed/34680740 http://dx.doi.org/10.3390/antibiotics10101158 |
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| author | Elshamy, Abdelsamed I. Mohamed, Tarik A. Elkady, Eman M. Saleh, Ibrahim A. El-Beih, Ahmed A. Alhammady, Montaser A. Ohta, Shinji Umeyama, Akemi Paré, Paul W. Hegazy, Mohamed-Elamir F. |
| author_facet | Elshamy, Abdelsamed I. Mohamed, Tarik A. Elkady, Eman M. Saleh, Ibrahim A. El-Beih, Ahmed A. Alhammady, Montaser A. Ohta, Shinji Umeyama, Akemi Paré, Paul W. Hegazy, Mohamed-Elamir F. |
| author_sort | Elshamy, Abdelsamed I. |
| collection | PubMed |
| description | The organic extracts of the Red Sea soft coral Paralemnalia thyrsoides has led to the identification of two neolemnane-type sesquiterpenoids: paralemnolins X and Y (1, 2). In addition to these newly characterized compounds, ten known metabolites (3–12) were isolated. Previously reported compounds were elucidated by literature comparison of spectroscopic data (1D and 2D NMR as well as MS data). In vitro antimicrobial activity was investigated for compounds (1–12) against Staphylococcus aureus, Escherichia coli, Candida albicans and Aspergillus niger. Compound 5 showed antimicrobial activity against all assayed microorganisms. |
| format | Online Article Text |
| id | pubmed-8532672 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2021 |
| publisher | MDPI |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-85326722021-10-23 Paralemnolins X and Y, New Antimicrobial Sesquiterpenoids from the Soft Coral Paralemnalia thyrsoide Elshamy, Abdelsamed I. Mohamed, Tarik A. Elkady, Eman M. Saleh, Ibrahim A. El-Beih, Ahmed A. Alhammady, Montaser A. Ohta, Shinji Umeyama, Akemi Paré, Paul W. Hegazy, Mohamed-Elamir F. Antibiotics (Basel) Article The organic extracts of the Red Sea soft coral Paralemnalia thyrsoides has led to the identification of two neolemnane-type sesquiterpenoids: paralemnolins X and Y (1, 2). In addition to these newly characterized compounds, ten known metabolites (3–12) were isolated. Previously reported compounds were elucidated by literature comparison of spectroscopic data (1D and 2D NMR as well as MS data). In vitro antimicrobial activity was investigated for compounds (1–12) against Staphylococcus aureus, Escherichia coli, Candida albicans and Aspergillus niger. Compound 5 showed antimicrobial activity against all assayed microorganisms. MDPI 2021-09-24 /pmc/articles/PMC8532672/ /pubmed/34680740 http://dx.doi.org/10.3390/antibiotics10101158 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
| spellingShingle | Article Elshamy, Abdelsamed I. Mohamed, Tarik A. Elkady, Eman M. Saleh, Ibrahim A. El-Beih, Ahmed A. Alhammady, Montaser A. Ohta, Shinji Umeyama, Akemi Paré, Paul W. Hegazy, Mohamed-Elamir F. Paralemnolins X and Y, New Antimicrobial Sesquiterpenoids from the Soft Coral Paralemnalia thyrsoide |
| title | Paralemnolins X and Y, New Antimicrobial Sesquiterpenoids from the Soft Coral Paralemnalia thyrsoide |
| title_full | Paralemnolins X and Y, New Antimicrobial Sesquiterpenoids from the Soft Coral Paralemnalia thyrsoide |
| title_fullStr | Paralemnolins X and Y, New Antimicrobial Sesquiterpenoids from the Soft Coral Paralemnalia thyrsoide |
| title_full_unstemmed | Paralemnolins X and Y, New Antimicrobial Sesquiterpenoids from the Soft Coral Paralemnalia thyrsoide |
| title_short | Paralemnolins X and Y, New Antimicrobial Sesquiterpenoids from the Soft Coral Paralemnalia thyrsoide |
| title_sort | paralemnolins x and y, new antimicrobial sesquiterpenoids from the soft coral paralemnalia thyrsoide |
| topic | Article |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8532672/ https://www.ncbi.nlm.nih.gov/pubmed/34680740 http://dx.doi.org/10.3390/antibiotics10101158 |
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