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Imipenem/Relebactam Ex Vivo Clearance during Continuous Renal Replacement Therapy

(1) Purpose of this study: determination of adsorption and transmembrane clearances (CL(TM)) of imipenem and relebactam in ex vivo continuous hemofiltration (CH) and continuous hemodialysis (CHD) models. These clearances were incorporated into a Monte Carlo Simulation (MCS), to develop drug dosing r...

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Detalles Bibliográficos
Autores principales:	Jang, Soo Min, Yessayan, Lenar, Dean, Michael, Costello, Gabrielle, Katwaru, Ravi, Mueller, Bruce A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8532761/ https://www.ncbi.nlm.nih.gov/pubmed/34680765 http://dx.doi.org/10.3390/antibiotics10101184

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