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Experimental Validation of a Mathematical Framework to Simulate Antibiotics with Distinct Half-Lives Concurrently in an In Vitro Model

Antimicrobial resistance has been steadily increasing in prevalence, and combination therapy is commonly used to treat infections due to multidrug resistant bacteria. Under certain circumstances, combination therapy of three or more drugs may be necessary, which makes it necessary to simulate the ph...

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Detalles Bibliográficos
Autores principales: Eales, Brianna M., Hudson, Cole S., Kesisoglou, Iordanis, Wang, Weiqun, Nikolaou, Michael, Tam, Vincent H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8532833/
https://www.ncbi.nlm.nih.gov/pubmed/34680836
http://dx.doi.org/10.3390/antibiotics10101256