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Antimicrobial Resistance Patterns in Diabetic Foot Infections, an Epidemiological Study in Northeastern Italy
This study is a retrospective epidemiological assessment of bacterial species isolated from a cohort of out-patients with diabetic foot infections referred to our “Diabetic Foot Unit” over one year, with particular attention to index pathogens, as identified by the EARS Network. Staphylococcus aureu...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8532857/ https://www.ncbi.nlm.nih.gov/pubmed/34680820 http://dx.doi.org/10.3390/antibiotics10101241 |
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author | Boschetti, Giovanni Sgarabotto, Dino Meloni, Marco Bruseghin, Marino Whisstock, Christine Marin, Mariagrazia Ninkovic, Sasa Pinfi, Michela Brocco, Enrico |
author_facet | Boschetti, Giovanni Sgarabotto, Dino Meloni, Marco Bruseghin, Marino Whisstock, Christine Marin, Mariagrazia Ninkovic, Sasa Pinfi, Michela Brocco, Enrico |
author_sort | Boschetti, Giovanni |
collection | PubMed |
description | This study is a retrospective epidemiological assessment of bacterial species isolated from a cohort of out-patients with diabetic foot infections referred to our “Diabetic Foot Unit” over one year, with particular attention to index pathogens, as identified by the EARS Network. Staphylococcus aureus and Pseudomonas aeruginosa accounted for 33.5% and 11.9% of cases, respectively. MRSA was isolated in 27.1% of patients, with 14.06% showing additional resistance to three antimicrobial classes. Pseudomonas aeruginosa presented extensive resistance to fluoroquinolones (57.3%), which was associated with resistance to piperacillin in 17.6% or to carbapenems in 23.5% of cases. Other pathogens, such as methicillin resistant Staphylococcus epidermidis, Escherichia coli and Morganella morganii ESBL and Enterococcus faecium VRE, were also found. |
format | Online Article Text |
id | pubmed-8532857 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-85328572021-10-23 Antimicrobial Resistance Patterns in Diabetic Foot Infections, an Epidemiological Study in Northeastern Italy Boschetti, Giovanni Sgarabotto, Dino Meloni, Marco Bruseghin, Marino Whisstock, Christine Marin, Mariagrazia Ninkovic, Sasa Pinfi, Michela Brocco, Enrico Antibiotics (Basel) Article This study is a retrospective epidemiological assessment of bacterial species isolated from a cohort of out-patients with diabetic foot infections referred to our “Diabetic Foot Unit” over one year, with particular attention to index pathogens, as identified by the EARS Network. Staphylococcus aureus and Pseudomonas aeruginosa accounted for 33.5% and 11.9% of cases, respectively. MRSA was isolated in 27.1% of patients, with 14.06% showing additional resistance to three antimicrobial classes. Pseudomonas aeruginosa presented extensive resistance to fluoroquinolones (57.3%), which was associated with resistance to piperacillin in 17.6% or to carbapenems in 23.5% of cases. Other pathogens, such as methicillin resistant Staphylococcus epidermidis, Escherichia coli and Morganella morganii ESBL and Enterococcus faecium VRE, were also found. MDPI 2021-10-13 /pmc/articles/PMC8532857/ /pubmed/34680820 http://dx.doi.org/10.3390/antibiotics10101241 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Boschetti, Giovanni Sgarabotto, Dino Meloni, Marco Bruseghin, Marino Whisstock, Christine Marin, Mariagrazia Ninkovic, Sasa Pinfi, Michela Brocco, Enrico Antimicrobial Resistance Patterns in Diabetic Foot Infections, an Epidemiological Study in Northeastern Italy |
title | Antimicrobial Resistance Patterns in Diabetic Foot Infections, an Epidemiological Study in Northeastern Italy |
title_full | Antimicrobial Resistance Patterns in Diabetic Foot Infections, an Epidemiological Study in Northeastern Italy |
title_fullStr | Antimicrobial Resistance Patterns in Diabetic Foot Infections, an Epidemiological Study in Northeastern Italy |
title_full_unstemmed | Antimicrobial Resistance Patterns in Diabetic Foot Infections, an Epidemiological Study in Northeastern Italy |
title_short | Antimicrobial Resistance Patterns in Diabetic Foot Infections, an Epidemiological Study in Northeastern Italy |
title_sort | antimicrobial resistance patterns in diabetic foot infections, an epidemiological study in northeastern italy |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8532857/ https://www.ncbi.nlm.nih.gov/pubmed/34680820 http://dx.doi.org/10.3390/antibiotics10101241 |
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