Cargando…

Patient Endothelial Colony-Forming Cells to Model Coronary Artery Disease Susceptibility and Unravel the Role of Dysregulated Mitochondrial Redox Signalling

Mechanisms involved in the individual susceptibility to atherosclerotic coronary artery disease (CAD) beyond traditional risk factors are poorly understood. Here, we describe the utility of cultured patient-derived endothelial colony-forming cells (ECFCs) in examining novel mechanisms of CAD suscept...

Descripción completa

Detalles Bibliográficos
Autores principales:	Besnier, Marie, Finemore, Meghan, Yu, Christine, Kott, Katharine A., Vernon, Stephen T., Seebacher, Nicole A., Genetzakis, Elijah, Furman, Anamarija, Tang, Owen, Davis, Ryan L., Hansen, Thomas, Psaltis, Peter J., Bubb, Kristen J., Wise, Steven G., Grieve, Stuart M., Di Bartolo, Belinda A., Figtree, Gemma A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8532880/ https://www.ncbi.nlm.nih.gov/pubmed/34679682 http://dx.doi.org/10.3390/antiox10101547

Ejemplares similares

Serum Soluble Lectin-like Oxidized Low-Density Lipoprotein Receptor-1 (sLOX-1) Is Associated with Atherosclerosis Severity in Coronary Artery Disease
por: Kott, Katharine A., et al.
Publicado: (2023)

Novel Strategies in the Early Detection and Treatment of Endothelial Cell-Specific Mitochondrial Dysfunction in Coronary Artery Disease
por: Lee, Weiqian E., et al.
Publicado: (2023)

Association of Global Coagulation Profiles With Cardiovascular Risk Factors and Atherosclerosis: A Sex Disaggregated Analysis From the BioHEART‐CT Study
por: Kott, Katharine A., et al.
Publicado: (2021)

β (3) Adrenergic Receptor Stimulation Promotes Reperfusion in Ischemic Limbs in a Murine Diabetic Model
por: Bubb, Kristen J., et al.
Publicado: (2021)

Biobanking for discovery of novel cardiovascular biomarkers using imaging-quantified disease burden: protocol for the longitudinal, prospective, BioHEART-CT cohort study
por: Kott, Katharine A, et al.
Publicado: (2019)

Single‐Cell Immune Profiling in Coronary Artery Disease: The Role of State‐of‐the‐Art Immunophenotyping With Mass Cytometry in the Diagnosis of Atherosclerosis
por: Kott, Katharine A., et al.
Publicado: (2020)

Protocol for the Stimulating β(3)-Adrenergic Receptors for Peripheral Artery Disease (STAR-PAD) trial: a double-blinded, randomised, placebo-controlled study evaluating the effects of mirabegron on functional performance in patients with peripheral arterial disease
por: Bubb, Kristen J, et al.
Publicado: (2021)

Mass cytometry analysis reveals altered immune profiles in patients with coronary artery disease
por: Kott, Katharine A, et al.
Publicado: (2023)

Metabolic Signatures in Coronary Artery Disease: Results from the BioHEART-CT Study
por: Vernon, Stephen T., et al.
Publicado: (2021)

The Translation and Commercialisation of Biomarkers for Cardiovascular Disease—A Review
por: Saleh, Soloman, et al.
Publicado: (2022)

A hierarchical approach to removal of unwanted variation for large-scale metabolomics data
por: Kim, Taiyun, et al.
Publicado: (2021)

Heart Failure with Reduced Ejection Fraction—Does Sex Matter?
por: Swaraj, Sascha, et al.
Publicado: (2021)

Lipidomics Profiling and Risk of Coronary Artery Disease in the BioHEART-CT Discovery Cohort
por: Zhu, Dantong, et al.
Publicado: (2023)

Biomarker Development in Cardiology: Reviewing the Past to Inform the Future
por: Kott, Katharine A., et al.
Publicado: (2022)

Mortality and Cardiovascular Outcomes in Patients Presenting With Non–ST Elevation Myocardial Infarction Despite No Standard Modifiable Risk Factors: Results From the SWEDEHEART Registry
por: Figtree, Gemma A., et al.
Publicado: (2022)

High‐Resolution Transthoracic Echocardiography Accurately Detects Pulmonary Arterial Pressure and Decreased Right Ventricular Contractility in a Mouse Model of Pulmonary Fibrosis and Secondary Pulmonary Hypertension
por: Hansen, Thomas S., et al.
Publicado: (2022)

Utility of cardiac magnetic resonance in assessing right-sided heart failure in sarcoidosis
por: Lønborg, Jacob, et al.
Publicado: (2013)

Glyphosate induces immune dysregulation in honey bees
por: Motta, Erick V. S., et al.
Publicado: (2022)

A disproportionate contribution of papillary muscles and trabeculations to total left ventricular mass makes choice of cardiovascular magnetic resonance analysis technique critical in Fabry disease
por: Kozor, Rebecca, et al.
Publicado: (2015)

Analysis of Mutations and Dysregulated Pathways Unravels Carcinogenic Effect and Clinical Actionability of Mutational Processes
por: Jiang, Zedong, et al.
Publicado: (2021)

Unraveling the links between neurodegeneration and Epstein-Barr virus-mediated cell cycle dysregulation
por: Tiwari, Deeksha, et al.
Publicado: (2022)

Regular Cocaine Use Is Associated with Increased Systolic Blood Pressure, Aortic Stiffness and Left Ventricular Mass in Young Otherwise Healthy Individuals
por: Kozor, Rebecca, et al.
Publicado: (2014)

Translating atherosclerosis research from bench to bedside: navigating the barriers for effective preclinical drug discovery
por: May, Lauren T., et al.
Publicado: (2022)

Metabolic Insights Into Infochemicals Induced Colony Formation and Flocculation in Scenedesmus subspicatus Unraveled by Quantitative Proteomics
por: Roccuzzo, Sebastiana, et al.
Publicado: (2020)

Automated Quantification of Myocardial Salvage in a Rat Model of Ischemia–Reperfusion Injury Using 3D High‐Resolution Magnetic Resonance Imaging (MRI)
por: Grieve, Stuart M., et al.
Publicado: (2014)

Unraveling the Molecular Mechanisms Underlying Complement Dysregulation by Nephritic Factors in C3G and IC-MPGN
por: Donadelli, Roberta, et al.
Publicado: (2018)

Cardiovascular magnetic resonance characteristics and clinical outcomes of patients with ST-elevation myocardial infarction and no standard modifiable risk factors–A DANAMI-3 substudy
por: Mazhar, Jawad, et al.
Publicado: (2022)

Unravelling Hitherto Unreported Masses Camouflaged as Pituitary Macro Adenomas
por: Velho, Vernon, et al.
Publicado: (2018)

High prevalence of Seoul hantavirus in a breeding colony of pet rats
por: McELHINNEY, L. M., et al.
Publicado: (2017)

Recent Advances in Enzymatic and Non-Enzymatic Electrochemical Glucose Sensing
por: Hassan, Mohamed H., et al.
Publicado: (2021)

Non-invasive Imaging in Women With Heart Failure — Diagnosis and Insights Into Disease Mechanisms
por: Kozor, Rebecca, et al.
Publicado: (2022)

Anacetrapib as a potential cardioprotective strategy
por: Di Bartolo, Belinda A, et al.
Publicado: (2017)

Highlights From Vascular Discovery: From Genes to Medicine Scientific Sessions 2018
por: Di Bartolo, Belinda A., et al.
Publicado: (2018)

The Colony for Cripples, Chailey
por: London, A. F.
Publicado: (1915)

Clinical Pathway for Coronary Atherosclerosis in Patients Without Conventional Modifiable Risk Factors: JACC State-of-the-Art Review
por: Figtree, Gemma A., et al.
Publicado: (2023)

Inhibition of Soluble Tumor Necrosis Factor Ameliorates Synaptic Alterations and Ca(2+) Dysregulation in Aged Rats
por: Sama, Diana M., et al.
Publicado: (2012)

Quadriceps Tendon Delamination Tear: A Case Report
por: Tsioupros, Alexandros, et al.
Publicado: (2023)

Reduced Innate Immune Response to a Staphylococcus aureus Small Colony Variant Compared to Its Wild-Type Parent Strain
por: Ou, Judy J. J., et al.
Publicado: (2016)

ptk7 mutant zebrafish models of congenital and idiopathic scoliosis implicate dysregulated Wnt signalling in disease
por: Hayes, Madeline, et al.
Publicado: (2014)

Overcoming cohort heterogeneity for the prediction of subclinical cardiovascular disease risk
por: Chan, Adam S., et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_aekus1vbplehnlorj2rlt9tifc