Antimicrobial Treatment Strategies for Stenotrophomonas maltophilia: A Focus on Novel Therapies

Stenotrophomonas maltophilia is an urgent global threat due to its increasing incidence and intrinsic antibiotic resistance. Antibiotic development has focused on carbapenem-resistant Enterobacteriaceae, Pseudomonas, and Acinetobacter, with approved antibiotics in recent years having limited activit...

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Detalles Bibliográficos
Autores principales: Gibb, Jean, Wong, Darren W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Systematic Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8532924/
https://www.ncbi.nlm.nih.gov/pubmed/34680807
http://dx.doi.org/10.3390/antibiotics10101226
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author Gibb, Jean
Wong, Darren W.
author_facet Gibb, Jean
Wong, Darren W.
author_sort Gibb, Jean
collection PubMed
description Stenotrophomonas maltophilia is an urgent global threat due to its increasing incidence and intrinsic antibiotic resistance. Antibiotic development has focused on carbapenem-resistant Enterobacteriaceae, Pseudomonas, and Acinetobacter, with approved antibiotics in recent years having limited activity for Stenotrophomonas. Accordingly, novel treatment strategies for Stenotrophomonas are desperately needed. We conducted a systemic literature review and offer recommendations based on current evidence for a treatment strategy of Stenotrophomonas infection.
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spelling pubmed-85329242021-10-23 Antimicrobial Treatment Strategies for Stenotrophomonas maltophilia: A Focus on Novel Therapies Gibb, Jean Wong, Darren W. Antibiotics (Basel) Systematic Review Stenotrophomonas maltophilia is an urgent global threat due to its increasing incidence and intrinsic antibiotic resistance. Antibiotic development has focused on carbapenem-resistant Enterobacteriaceae, Pseudomonas, and Acinetobacter, with approved antibiotics in recent years having limited activity for Stenotrophomonas. Accordingly, novel treatment strategies for Stenotrophomonas are desperately needed. We conducted a systemic literature review and offer recommendations based on current evidence for a treatment strategy of Stenotrophomonas infection. MDPI 2021-10-09 /pmc/articles/PMC8532924/ /pubmed/34680807 http://dx.doi.org/10.3390/antibiotics10101226 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Systematic Review
Gibb, Jean
Wong, Darren W.
Antimicrobial Treatment Strategies for Stenotrophomonas maltophilia: A Focus on Novel Therapies
title Antimicrobial Treatment Strategies for Stenotrophomonas maltophilia: A Focus on Novel Therapies
title_full Antimicrobial Treatment Strategies for Stenotrophomonas maltophilia: A Focus on Novel Therapies
title_fullStr Antimicrobial Treatment Strategies for Stenotrophomonas maltophilia: A Focus on Novel Therapies
title_full_unstemmed Antimicrobial Treatment Strategies for Stenotrophomonas maltophilia: A Focus on Novel Therapies
title_short Antimicrobial Treatment Strategies for Stenotrophomonas maltophilia: A Focus on Novel Therapies
title_sort antimicrobial treatment strategies for stenotrophomonas maltophilia: a focus on novel therapies
topic Systematic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8532924/
https://www.ncbi.nlm.nih.gov/pubmed/34680807
http://dx.doi.org/10.3390/antibiotics10101226
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