Cargando…

Crucial Role of Reactive Oxygen Species (ROS) for the Proapoptotic Effects of Indirubin Derivatives in Cutaneous SCC Cells

Efficient drugs are needed for countering the worldwide high incidence of cutaneous squamous cell carcinoma (cSCC) and actinic keratosis. Indirubin derivatives represent promising candidates, but their effects in cSCC cells have not been reported before. Here, we investigated the efficacy of three i...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhu, Jiaqi, Langer, Peter, Ulrich, Claas, Eberle, Jürgen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8532942/ https://www.ncbi.nlm.nih.gov/pubmed/34679649 http://dx.doi.org/10.3390/antiox10101514

Ejemplares similares

Key Role of Reactive Oxygen Species (ROS) in Indirubin Derivative-Induced Cell Death in Cutaneous T-Cell Lymphoma Cells
por: Soltan, Marwa Y., et al.
Publicado: (2019)

High ROS Production by Celecoxib and Enhanced Sensitivity for Death Ligand-Induced Apoptosis in Cutaneous SCC Cell Lines
por: Zhu, Jiaqi, et al.
Publicado: (2021)

Inhibition of Cell Proliferation and Cell Viability by Sinecatechins in Cutaneous SCC Cells Is Related to an Imbalance of ROS and Loss of Mitochondrial Membrane Potential
por: Zhu, Jiaqi, et al.
Publicado: (2022)

Indirubin and Indirubin Derivatives for Counteracting Proliferative Diseases
por: Blažević, Tina, et al.
Publicado: (2015)

Critical role of reactive oxygen species (ROS) for synergistic enhancement of apoptosis by vemurafenib and the potassium channel inhibitor TRAM-34 in melanoma cells
por: Bauer, Daniel, et al.
Publicado: (2017)

An Indirubin Derivative, Indirubin-3′-Monoxime Suppresses Oral Cancer Tumorigenesis through the Downregulation of Survivin
por: Lo, Wan-Yu, et al.
Publicado: (2013)

Subcellular Reactive Oxygen Species (ROS) in Cardiovascular Pathophysiology
por: Aldosari, Sarah, et al.
Publicado: (2018)

Indirubin derivative E804 inhibits angiogenesis
por: Shin, Eun-Kyung, et al.
Publicado: (2012)

Cellular death, reactive oxygen species (ROS) and diabetic complications
por: Volpe, Caroline Maria Oliveira, et al.
Publicado: (2018)

Sulforaphane Impact on Reactive Oxygen Species (ROS) in Bladder Carcinoma
por: Xie, Hui, et al.
Publicado: (2021)

Deconvoluting the Complexity of Reactive Oxygen Species (ROS) in Neurodegenerative Diseases
por: Zhou, Yuxin, et al.
Publicado: (2022)

Targeting Cutaneous T-Cell Lymphoma Cells by Ingenol Mebutate (PEP005) Correlates with PKCδ Activation, ROS Induction as Well as Downregulation of XIAP and c-FLIP
por: Sumarni, Uly, et al.
Publicado: (2021)

Cutaneous squamous cell carcinoma (SCC) arising in stump of amputated finger in a patient with resected glossal SCC
por: Uchida, Kenzo, et al.
Publicado: (2012)

Reactive Oxygen Species and Nitric Oxide in Cutaneous Leishmaniasis
por: Horta, Maria Fátima, et al.
Publicado: (2012)

Small Molecules in the Treatment of Squamous Cell Carcinomas: Focus on Indirubins
por: Schäfer, Mirijam, et al.
Publicado: (2021)

The Role of Reactive Oxygen Species (ROS) in the Biological Activities of Metallic Nanoparticles
por: Abdal Dayem, Ahmed, et al.
Publicado: (2017)

Reactive Oxygen Species (ROS): Beneficial Companions of Plants’ Developmental Processes
por: Singh, Rachana, et al.
Publicado: (2016)

Nanotherapy and Reactive Oxygen Species (ROS) in Cancer: A Novel Perspective
por: Brenneisen, Peter, et al.
Publicado: (2018)

Reactive Oxygen Species (ROS), Intimal Thickening, and Subclinical Atherosclerotic Disease
por: Burtenshaw, Denise, et al.
Publicado: (2019)

Editorial: Reactive Oxygen Species (ROS) Detection Methods in Biological System
por: Prasad, Ankush, et al.
Publicado: (2019)

Mitochondrial Reactive Oxygen Species (ROS) Production Alters Sperm Quality
por: Chianese, Rosanna, et al.
Publicado: (2021)

Editorial: Reactive oxygen species (ROS) signaling during cytoskeleton dynamics
por: Nakao, Lia S., et al.
Publicado: (2023)

A Sensitive LC-MS/MS Method for the Simultaneous Determination of Two Thia-Analogous Indirubin N-Glycosides and Indirubin-3′-Monoxime in Plasma and Cell Culture Medium
por: Fischle, Alica, et al.
Publicado: (2022)

A Thia-Analogous Indirubin N-Glycoside Disrupts Mitochondrial Function and Causes the Death of Human Melanoma and Cutaneous Squamous Cell Carcinoma Cells
por: Wendt, Franziska, et al.
Publicado: (2023)

Interplay Between Reactive Oxygen Species and the Inflammasome Are Crucial for Restriction of Neospora caninum Replication
por: Mota, Caroline M., et al.
Publicado: (2020)

HTLV-1 Tax1 represses the proapoptotic protein Bim, which is crucial for T-cell transformation
por: Higuchi, Masaya, et al.
Publicado: (2011)

Indirubin derivatives are potent and selective anti-Trypanosoma cruzi agents
por: Efstathiou, Antonia, et al.
Publicado: (2018)

The Role of Reactive Oxygen Species (ROS) in the Formation of Extracellular Traps (ETs) in Humans
por: Stoiber, Walter, et al.
Publicado: (2015)

Reactive Oxygen Species (ROS) and Nucleic Acid Modifications During Seed Dormancy
por: Katsuya-Gaviria, Kai, et al.
Publicado: (2020)

Reactive Oxygen Species (ROS)-Responsive Nanomedicine for Solving Ischemia-Reperfusion Injury
por: Chen, Weiyu, et al.
Publicado: (2020)

Reactive Oxygen Species (ROS)-Sensitive Prodrugs of the Tyrosine Kinase Inhibitor Crizotinib
por: Bielec, Bjoern, et al.
Publicado: (2020)

Reactive oxygen species (ROS)-responsive nanoprobe for bioimaging and targeting therapy of osteoarthritis
por: Shen, Chong, et al.
Publicado: (2021)

Reactive Oxygen Species (ROS)-Responsive Biomaterials for the Treatment of Bone-Related Diseases
por: Ren, Xiaoxiang, et al.
Publicado: (2022)

Overexpression of the Axl tyrosine kinase receptor in cutaneous SCC-derived cell lines and tumours
por: Green, J, et al.
Publicado: (2006)

Antitumor Effect of Albendazole on Cutaneous Squamous Cell Carcinoma (SCC) Cells
por: Zhang, Qing-Ling, et al.
Publicado: (2019)

Candida albicans Reactive Oxygen Species (ROS)-Dependent Lethality and ROS-Independent Hyphal and Biofilm Inhibition by Eugenol and Citral
por: Shahina, Zinnat, et al.
Publicado: (2022)

The Future Challenge of Reactive Oxygen Species (ROS) in Hypertension: From Bench to Bed Side
por: Togliatto, Gabriele, et al.
Publicado: (2017)

Sucralose promotes accumulation of reactive oxygen species (ROS) and adipogenesis in mesenchymal stromal cells
por: Kundu, Nabanita, et al.
Publicado: (2020)

Reactive Oxygen Species (ROS) and Antioxidants as Immunomodulators in Exercise: Implications for Heme Oxygenase and Bilirubin
por: Thomas, David Travis, et al.
Publicado: (2022)

Intertwined Roles of Reactive Oxygen Species and Salicylic Acid Signaling Are Crucial for the Plant Response to Biotic Stress
por: Lukan, Tjaša, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_95mnacobndcp6ot422bhm0jd01