Usefulness of Interleukin-18 as a Diagnostic Biomarker to Differentiate Adult-Onset Still’s Disease With/Without Macrophage Activation Syndrome From Other Secondary Hemophagocytic Lymphohistiocytosis in Adults

BACKGROUND: Interleukin (IL)-18 is markedly elevated in systemic inflammatory diseases that cause the ‘cytokine storm’ such as adult-onset Still’s disease (AOSD) and hemophagocytic lymphohistiocytosis (HLH). The differences in IL-18 between AOSD and HLH, especially in adults, is uncertain. Macrophag...

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Detalles Bibliográficos
Autores principales: Shiga, Toshihiko, Nozaki, Yuji, Tomita, Daisuke, Kishimoto, Kazuya, Hirooka, Yasuaki, Kinoshita, Koji, Funauchi, Masanori, Matsumura, Itaru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8533049/
https://www.ncbi.nlm.nih.gov/pubmed/34691064
http://dx.doi.org/10.3389/fimmu.2021.750114

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