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The Interactions of H(2)TMPyP, Analogues and Its Metal Complexes with DNA G-Quadruplexes—An Overview

The evidence that telomerase is overexpressed in almost 90% of human cancers justifies the proposal of this enzyme as a potential target for anticancer drug design. The inhibition of telomerase by quadruplex stabilizing ligands is being considered a useful approach in anticancer drug design proposal...

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Detalles Bibliográficos
Autores principales: Ramos, Catarina I. V., Monteiro, Ana R., Moura, Nuno M. M., Faustino, Maria Amparo F., Trindade, Tito, Neves, Maria Graça P. M. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8533071/
https://www.ncbi.nlm.nih.gov/pubmed/34680037
http://dx.doi.org/10.3390/biom11101404