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Salvianolic Acid C Protects against Cisplatin-Induced Acute Kidney Injury through Attenuation of Inflammation, Oxidative Stress and Apoptotic Effects and Activation of the CaMKK–AMPK–Sirt1-Associated Signaling Pathway in Mouse Models
Acute kidney injury (AKI) is a sudden reduction in kidney activity and has a high mortality rate. Salvianolic acid C (SAC), one of the main polyphenolic components of Salvia miltiorrhiza, displays significant pharmacologically active effects. An animal model of cisplatin-induced kidney injury was us...
Autores principales: | Chien, Liang-Hsuan, Wu, Chien-Ta, Deng, Jeng-Shyan, Jiang, Wen-Ping, Huang, Wen-Chin, Huang, Guan-Jhong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8533075/ https://www.ncbi.nlm.nih.gov/pubmed/34679755 http://dx.doi.org/10.3390/antiox10101620 |
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