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HMG-CoA Reductase Inhibitor, Simvastatin Is Effective in Decreasing Degree of Myocarditis by Inhibiting Metalloproteinases Activation
Background: Acute myocarditis often progresses to heart failure because there is no effective, etiology-targeted therapy of this disease. Simvastatin has been shown to be cardioprotective by decreasing matrix metalloproteinases’ (MMPs) activity. The study was designed to determine whether simvastati...
Autores principales: | Skrzypiec-Spring, Monika, Sapa-Wojciechowska, Agnieszka, Haczkiewicz-Leśniak, Katarzyna, Piasecki, Tomasz, Kwiatkowska, Joanna, Podhorska-Okołów, Marzenna, Szeląg, Adam |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8533153/ https://www.ncbi.nlm.nih.gov/pubmed/34680049 http://dx.doi.org/10.3390/biom11101415 |
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