Alcohol Metabolism Enriches Squamous Cell Carcinoma Cancer Stem Cells That Survive Oxidative Stress via Autophagy

Background: Alcohol (ethanol) consumption is a major risk factor for head and neck and esophageal squamous cell carcinomas (SCCs). However, how ethanol (EtOH) affects SCC homeostasis is incompletely understood. Methods: We utilized three-dimensional (3D) organoids and xenograft tumor transplantation...

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Detalles Bibliográficos
Autores principales: Shimonosono, Masataka, Tanaka, Koji, Flashner, Samuel, Takada, Satoshi, Matsuura, Norihiro, Tomita, Yasuto, Sachdeva, Uma M., Noguchi, Eishi, Sangwan, Veena, Ferri, Lorenzo, Momen-Heravi, Fatemeh, Yoon, Angela J., Klein-Szanto, Andres J., Diehl, J. Alan, Nakagawa, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8533166/
https://www.ncbi.nlm.nih.gov/pubmed/34680112
http://dx.doi.org/10.3390/biom11101479

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8533166/
https://www.ncbi.nlm.nih.gov/pubmed/34680112
http://dx.doi.org/10.3390/biom11101479

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