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Alcohol Metabolism Enriches Squamous Cell Carcinoma Cancer Stem Cells That Survive Oxidative Stress via Autophagy
Background: Alcohol (ethanol) consumption is a major risk factor for head and neck and esophageal squamous cell carcinomas (SCCs). However, how ethanol (EtOH) affects SCC homeostasis is incompletely understood. Methods: We utilized three-dimensional (3D) organoids and xenograft tumor transplantation...
Autores principales: | Shimonosono, Masataka, Tanaka, Koji, Flashner, Samuel, Takada, Satoshi, Matsuura, Norihiro, Tomita, Yasuto, Sachdeva, Uma M., Noguchi, Eishi, Sangwan, Veena, Ferri, Lorenzo, Momen-Heravi, Fatemeh, Yoon, Angela J., Klein-Szanto, Andres J., Diehl, J. Alan, Nakagawa, Hiroshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8533166/ https://www.ncbi.nlm.nih.gov/pubmed/34680112 http://dx.doi.org/10.3390/biom11101479 |
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