Histochrome Attenuates Myocardial Ischemia-Reperfusion Injury by Inhibiting Ferroptosis-Induced Cardiomyocyte Death

Reactive oxygen species (ROS) and intracellular iron levels are critical modulators of lipid peroxidation that trigger iron-dependent non-apoptotic ferroptosis in myocardial ischemia-reperfusion (I/R) injury. Histochrome (HC), with a potent antioxidant moiety and iron-chelating capacity, is now avai...

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Detalles Bibliográficos
Autores principales: Hwang, Ji-Won, Park, Jae-Hyun, Park, Bong-Woo, Kim, Hyeok, Kim, Jin-Ju, Sim, Woo-Sup, Mishchenko, Natalia P., Fedoreyev, Sergey A., Vasileva, Elena A., Ban, Kiwon, Park, Hun-Jun, Baek, Sang-Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8533175/
https://www.ncbi.nlm.nih.gov/pubmed/34679760
http://dx.doi.org/10.3390/antiox10101624

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8533175/
https://www.ncbi.nlm.nih.gov/pubmed/34679760
http://dx.doi.org/10.3390/antiox10101624

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