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Histochrome Attenuates Myocardial Ischemia-Reperfusion Injury by Inhibiting Ferroptosis-Induced Cardiomyocyte Death
Reactive oxygen species (ROS) and intracellular iron levels are critical modulators of lipid peroxidation that trigger iron-dependent non-apoptotic ferroptosis in myocardial ischemia-reperfusion (I/R) injury. Histochrome (HC), with a potent antioxidant moiety and iron-chelating capacity, is now avai...
Autores principales: | Hwang, Ji-Won, Park, Jae-Hyun, Park, Bong-Woo, Kim, Hyeok, Kim, Jin-Ju, Sim, Woo-Sup, Mishchenko, Natalia P., Fedoreyev, Sergey A., Vasileva, Elena A., Ban, Kiwon, Park, Hun-Jun, Baek, Sang-Hong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8533175/ https://www.ncbi.nlm.nih.gov/pubmed/34679760 http://dx.doi.org/10.3390/antiox10101624 |
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