Bile Duct Ligation Upregulates Expression and Function of L-Amino Acid Transporter 1 at Blood–Brain Barrier of Rats via Activation of Aryl Hydrocarbon Receptor by Bilirubin

Liver failure is associated with increased levels of brain aromatic amino acids (AAAs), whose transport across the blood–brain barrier (BBB) is mainly mediated by L-amino acid transporter 1 (LAT1). We aimed to investigate whether liver failure induced by bile duct ligation (BDL) increases levels of...

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Detalles Bibliográficos
Autores principales: Zheng, Xiaoke, Yang, Hanyu, Qin, Lan, Wang, Siqian, Xie, Lei, Yang, Lu, Kong, Weimin, Zhu, Liang, Liu, Li, Liu, Xiaodong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8533316/
https://www.ncbi.nlm.nih.gov/pubmed/34680437
http://dx.doi.org/10.3390/biomedicines9101320

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8533316/
https://www.ncbi.nlm.nih.gov/pubmed/34680437
http://dx.doi.org/10.3390/biomedicines9101320

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