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Bile Duct Ligation Upregulates Expression and Function of L-Amino Acid Transporter 1 at Blood–Brain Barrier of Rats via Activation of Aryl Hydrocarbon Receptor by Bilirubin
Liver failure is associated with increased levels of brain aromatic amino acids (AAAs), whose transport across the blood–brain barrier (BBB) is mainly mediated by L-amino acid transporter 1 (LAT1). We aimed to investigate whether liver failure induced by bile duct ligation (BDL) increases levels of...
Autores principales: | Zheng, Xiaoke, Yang, Hanyu, Qin, Lan, Wang, Siqian, Xie, Lei, Yang, Lu, Kong, Weimin, Zhu, Liang, Liu, Li, Liu, Xiaodong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8533316/ https://www.ncbi.nlm.nih.gov/pubmed/34680437 http://dx.doi.org/10.3390/biomedicines9101320 |
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